Human Beta-Arrestin 1/ARRB1 Recombinant Protein (RPES3444)

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주문
SKU:
RPES3444
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human Beta-Arrestin 1/ARRB1 Recombinant Protein

β-Arrestin-1 (ARRB1) is a cytoplasmic protein that belongs to the arrestin family. ARRB1 is expressed at high levels in peripheral blood leukocytes and the central nervous system. ARRB1 regulates agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. ARRB1 acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. ARRB1 is believed to play a major role in regulating receptor-mediated immune functions. ARRB1 is involved in Toll-like receptor and IL-1 receptor signaling through the interaction with TRAF6.

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