GC Antibody (PACO32424)
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주문- SKU:
- PACO32424
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GC Antibody (PACO32424) |
Antibody SKU: | PACO32424 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Vitamin D-binding protein (19-474AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: GC antibody at 2µg/ml + A549 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 53, 40, 56 kDa Observed band size: 53 kDa . | |
Immunohistochemistry of paraffin-embedded human liver cancer using PACO32424 at dilution of 1:100. |
Background: | Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes. |
Synonyms: | Vitamin D-binding protein (DBP) (VDB) (Gc protein-derived macrophage activating factor) (Gc-MAF) (GcMAF) (Gc-globulin) (Group-specific component) (Gc) (Vitamin D-binding protein-macrophage activating factor) (DBP-maf), GC |
UniProt Protein Function: | GC: Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes. Belongs to the ALB/AFP/VDB family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 4q12-q13 Cellular Component: cytosol; extracellular region; extracellular space; lysosomal lumen Molecular Function:actin binding; vitamin D binding Biological Process: vitamin D metabolic process Disease: Graves Disease, Susceptibility To, 1 |
NCBI Summary: | The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011] |
UniProt Code: | P02774 |
NCBI GenInfo Identifier: | 139641 |
NCBI Gene ID: | 2638 |
NCBI Accession: | P02774.1 |
UniProt Secondary Accession: | P02774,Q16309, Q16310, Q53F31, Q6GTG1, B4DPP2, D6RAK8 |
UniProt Related Accession: | P02774 |
Molecular Weight: | 55,123 Da |
NCBI Full Name: | Vitamin D-binding protein |
NCBI Synonym Full Names: | GC, vitamin D binding protein |
NCBI Official Symbol: | GC |
NCBI Official Synonym Symbols: | DBP; GRD3; VDBG; VDBP; GcMAF; DBP/GC; Gc-MAF; HEL-S-51 |
NCBI Protein Information: | vitamin D-binding protein |
UniProt Protein Name: | Vitamin D-binding protein |
UniProt Synonym Protein Names: | Gc protein-derived macrophage activating factor |
Protein Family: | GCR1-dependent translation factor |
UniProt Gene Name: | GC |
UniProt Entry Name: | VTDB_HUMAN |
Antibodies | ELISA Kits |
Anti-GC Antibody (CAB5709) | Human DBP (Vitamin D Binding Protein) CLIA Kit (HUES00914) |
GC Antibody (PACO06423) | Human Vitamin D-binding protein (GC) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |