UGCG Antibody (PACO14458)
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주문- SKU:
- PACO14458
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | UGCG Antibody (PACO14458) |
Antibody SKU: | PACO14458 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human UGCG |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: A431 cells, Primary antibody: PACO14458(UGCG Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO14458(UGCG Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation. |
Synonyms: | UDP-glucose ceramide glucosyltransferase |
UniProt Protein Function: | UGCG: Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a flippase. Belongs to the glycosyltransferase 2 family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transferase; EC 2.4.1.80; Lipid Metabolism - sphingolipid Chromosomal Location of Human Ortholog: 9q31 Cellular Component: Golgi membrane; membrane; integral to membrane Molecular Function:ceramide glucosyltransferase activity Biological Process: epidermis development; glycosphingolipid biosynthetic process; sphingolipid metabolic process; glycosphingolipid metabolic process; glucosylceramide biosynthetic process |
NCBI Summary: | This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids. [provided by RefSeq, Dec 2014] |
UniProt Code: | Q16739 |
NCBI GenInfo Identifier: | 2498228 |
NCBI Gene ID: | 7357 |
NCBI Accession: | Q16739.1 |
UniProt Secondary Accession: | Q16739,Q5T258, |
UniProt Related Accession: | Q16739 |
Molecular Weight: | |
NCBI Full Name: | Ceramide glucosyltransferase |
NCBI Synonym Full Names: | UDP-glucose ceramide glucosyltransferase |
NCBI Official Symbol: | UGCG |
NCBI Official Synonym Symbols: | GCS; GLCT1 |
NCBI Protein Information: | ceramide glucosyltransferase; glucosylceramide synthase; UDP-glucose:N-acylsphingosine D-glucosyltransferase |
UniProt Protein Name: | Ceramide glucosyltransferase |
UniProt Synonym Protein Names: | GLCT-1; Glucosylceramide synthase; GCS; UDP-glucose ceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferase |
Protein Family: | Ceramide glucosyltransferase |
UniProt Gene Name: | UGCG |
UniProt Entry Name: | CEGT_HUMAN |
Antibodies | ELISA Kits |
Anti-UGCG Antibody (CAB6317) | Human UGCG ELISA Kit |
UGCG Antibody (PACO13075) | Human Ceramide glucosyltransferase (UGCG) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |