GALT Antibody (PACO16392)
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주문- SKU:
- PACO16392
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GALT Antibody (PACO16392) |
Antibody SKU: | PACO16392 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human GALT |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO16392(GALT Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal liver tissue, Primary antibody: PACO16392(GALT Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO16392(GALT Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene. |
Synonyms: | galactose-1-phosphate uridylyltransferase |
UniProt Protein Function: | GALT: Defects in GALT are the cause of galactosemia (GALCT). Galactosemia is an inherited disorder of galactose metabolism that causes jaundice, cataracts, and mental retardation. Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. |
UniProt Protein Details: | Protein type:EC 2.7.7.12; Carbohydrate Metabolism - galactose; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Motility/polarity/chemotaxis; Transferase Chromosomal Location of Human Ortholog: 9p13 Cellular Component: cytosol; Golgi apparatus Molecular Function:protein binding; UDP-glucose:hexose-1-phosphate uridylyltransferase activity Biological Process: galactose catabolic process; galactose metabolic process Disease: Galactosemia |
NCBI Summary: | Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
UniProt Code: | P07902 |
NCBI GenInfo Identifier: | 3183522 |
NCBI Gene ID: | 2592 |
NCBI Accession: | P07902.3 |
UniProt Secondary Accession: | P07902,Q14355, Q14356, Q14357, Q14358, Q14359, Q14360 Q14361, Q14363, Q14364, B4E097, E7ET32, |
UniProt Related Accession: | P07902 |
Molecular Weight: | 31,107 Da |
NCBI Full Name: | Galactose-1-phosphate uridylyltransferase |
NCBI Synonym Full Names: | galactose-1-phosphate uridylyltransferase |
NCBI Official Symbol: | GALT |
NCBI Protein Information: | galactose-1-phosphate uridylyltransferase |
UniProt Protein Name: | Galactose-1-phosphate uridylyltransferase |
UniProt Synonym Protein Names: | UDP-glucose--hexose-1-phosphate uridylyltransferase |
Protein Family: | Gallate transporter |
UniProt Gene Name: | GALT |
UniProt Entry Name: | GALT_HUMAN |
Antibodies |
Anti-GALT Antibody (CAB6292) |
Anti-GALT Antibody (CAB19903)[KO Validated] |
GALT Antibody (PACO09407) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |