B4GALT6 Antibody (PACO63499)
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주문- SKU:
- PACO63499
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | B4GALT6 Antibody (PACO63499) |
Antibody SKU: | PACO63499 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Beta-1,4-galactosyltransferase 6 protein (70-280AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: A549 whole cell lysate, U251 whole cell lysate. All lanes: B4GALT6 antibody at 1:1000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 45, 41 kDa. Observed band size: 45 kDa. |
Background: | Required for the biosynthesis of glycosphingolipids. |
Synonyms: | Beta-1,4-galactosyltransferase 6 (Beta-1,4-GalTase 6) (Beta4Gal-T6) (b4Gal-T6) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6) [Includes: Glucosylceramide beta-1,4-galactosyltransferase (EC 2.4.1.274) (Lactosylceramide synthase) (LacCer synthase) (UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase)], B4GALT6 |
UniProt Protein Function: | B4GALT6: Required for the biosynthesis of glycosphingolipids. Belongs to the glycosyltransferase 7 family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; EC 2.4.1.274; Lipid Metabolism - sphingolipid; Transferase Chromosomal Location of Human Ortholog: 18q11 Cellular Component: Golgi membrane Molecular Function:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; galactosyltransferase activity Biological Process: keratan sulfate biosynthetic process |
NCBI Summary: | This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UBX8 |
NCBI GenInfo Identifier: | 13123991 |
NCBI Gene ID: | 9331 |
NCBI Accession: | Q9UBX8.1 |
UniProt Secondary Accession: | Q9UBX8,O60514, Q6NT09, |
UniProt Related Accession: | Q9UBX8 |
Molecular Weight: | 40,127 Da |
NCBI Full Name: | Beta-1,4-galactosyltransferase 6 |
NCBI Synonym Full Names: | beta-1,4-galactosyltransferase 6 |
NCBI Official Symbol: | B4GALT6 |
NCBI Official Synonym Symbols: | B4Gal-T6; beta4Gal-T6 |
NCBI Protein Information: | beta-1,4-galactosyltransferase 6 |
UniProt Protein Name: | Beta-1,4-galactosyltransferase 6 |
UniProt Synonym Protein Names: | Lactosylceramide synthase; LacCer synthase; UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase |
Protein Family: | Beta-1,4-galactosyltransferase |
UniProt Gene Name: | B4GALT6 |
UniProt Entry Name: | B4GT6_HUMAN |
Antibodies |
Anti-B4GALT6 Antibody (CAB17047) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |