FCGR2A Antibody (PACO47762)
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주문- SKU:
- PACO47762
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | FCGR2A Antibody (PACO47762) |
Antibody SKU: | PACO47762 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Low affinity immunoglobulin γ Fc region receptor II-a protein (241-317AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Mouse spleen tissue. All lanes: FCGR2A antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 36, 35 kDa. Observed band size: 36 kDa.. | |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO47762 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human gastric cancer using PACO47762 at dilution of 1:100. |
Background: | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. |
Synonyms: | Low affinity immunoglobulin γ Fc region receptor II-a (IgG Fc receptor II-a) (CDw32) (Fc-γ RII-a) (Fc-gamma-RIIa) (FcRII-a) (CD antigen CD32), FCGR2A, CD32 FCG2 FCGR2A1 IGFR2 |
UniProt Protein Function: | FCGR2A: low affinity receptor for the Fc region of IgGs. Binding to IgG initiates cellular responses against pathogens and soluble antigens. A type I membrane protein found on monocytes, neutrophils and platelets. SHP-1 associates with this protein to modulate signaling events in myeloid cells. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, misc.; Cell surface Chromosomal Location of Human Ortholog: 1q23 Cellular Component: plasma membrane Molecular Function:protein binding Disease: Malaria, Susceptibility To; Systemic Lupus Erythematosus |
NCBI Summary: | This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008] |
UniProt Code: | P12318 |
NCBI GenInfo Identifier: | 160332371 |
NCBI Gene ID: | 2212 |
NCBI Accession: | P12318.4 |
UniProt Secondary Accession: | P12318,Q8WUN1, Q8WW64, |
UniProt Related Accession: | P12318 |
Molecular Weight: | 34,930 Da |
NCBI Full Name: | Low affinity immunoglobulin gamma Fc region receptor II-a |
NCBI Synonym Full Names: | Fc fragment of IgG receptor IIa |
NCBI Official Symbol: | FCGR2A |
NCBI Official Synonym Symbols: | CD32; FCG2; FcGR; CD32A; CDw32; FCGR2; IGFR2; FCGR2A1 |
NCBI Protein Information: | low affinity immunoglobulin gamma Fc region receptor II-a |
UniProt Protein Name: | Low affinity immunoglobulin gamma Fc region receptor II-a |
UniProt Synonym Protein Names: | CDw32; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a; CD_antigen: CD32 |
Protein Family: | Low affinity immunoglobulin gamma Fc region receptor |
UniProt Gene Name: | FCGR2A |
UniProt Entry Name: | FCG2A_HUMAN |
Antibodies | ELISA Kits |
Anti-FCGR2A Antibody (CAB1388) | Human CD32 / FcGR2 ELISA Kit |
FCGR2A Antibody (PACO06869) | |
FCGR2A Antibody (PACO09266) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |