DIMT1 Antibody (PACO42490)
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주문- SKU:
- PACO42490
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DIMT1 Antibody (PACO42490) |
Antibody SKU: | PACO42490 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Probable dimethyladenosine transferase protein (1-313AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: DIMT1 antibody at 2µg/ml + Mouse thymus tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 35 kDa. Observed band size: 35 kDa. | |
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO42490 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO42490 at dilution of 1:100. |
Background: | pecifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. |
Synonyms: | Probable dimethyladenosine transferase (EC 2.1.1.183) (DIM1 dimethyladenosine transferase 1 homolog) (DIM1 dimethyladenosine transferase 1-like) (Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase) (Probable 18S rRNA dimethylase) (Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase), DIMT1, DIMT1L |
UniProt Protein Function: | DIMT1: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. |
UniProt Protein Details: | Protein type:EC 2.1.1.183; Nucleolus; RNA-binding; Methyltransferase Chromosomal Location of Human Ortholog: 5q12.1 Cellular Component: cytoplasm; nucleolus; nucleus Molecular Function:rRNA (adenine-N6,N6-)-dimethyltransferase activity Biological Process: rRNA methylation |
NCBI Summary: | The protein encoded by this gene is a methyltransferase that is responsible for dimethylation of adjacent adenosines near the 18S rRNA decoding site. The encoded protein is essential for ribosome biogenesis, although its catalytic activity is not involved in the process. The yeast ortholog of this protein functions in the cytoplasm while this protein functions in the nucleus. [provided by RefSeq, Jan 2017] |
UniProt Code: | Q9UNQ2 |
NCBI GenInfo Identifier: | 27151492 |
NCBI Gene ID: | 27292 |
NCBI Accession: | Q9UNQ2.1 |
UniProt Related Accession: | Q9UNQ2 |
Molecular Weight: | 35 kDa |
NCBI Full Name: | Probable dimethyladenosine transferase |
NCBI Synonym Full Names: | DIMT1 rRNA methyltransferase and ribosome maturation factor |
NCBI Official Symbol: | DIMT1 |
NCBI Official Synonym Symbols: | DIM1; DIMT1L; HUSSY5; HSA9761 |
NCBI Protein Information: | probable dimethyladenosine transferase |
UniProt Protein Name: | Probable dimethyladenosine transferase |
UniProt Synonym Protein Names: | DIM1 dimethyladenosine transferase 1 homolog; DIM1 dimethyladenosine transferase 1-like; Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase; Probable 18S rRNA dimethylase; Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase |
Protein Family: | Probable dimethyladenosine transferase |
UniProt Gene Name: | DIMT1 |
UniProt Entry Name: | DIM1_HUMAN |
Antibodies |
Anti-DIMT1 Antibody (CAB7589) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |