CIAO1 Antibody (PACO44617)
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주문- SKU:
- PACO44617
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CIAO1 Antibody (PACO44617) |
Antibody SKU: | PACO44617 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Probable cytosolic iron-sulfur protein assembly protein CIAO1 protein (1-339AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO44617 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human testis tissue using PACO44617 at dilution of 1:100. |
Background: | Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation. |
Synonyms: | Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39), CIAO1, WDR39 |
UniProt Protein Function: | CIAO1: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation. Belongs to the WD repeat CIA1 family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 2q11.2 Biological Process: regulation of transcription from RNA polymerase II promoter; iron-sulfur cluster assembly; positive regulation of cell proliferation; chromosome segregation |
UniProt Code: | O76071 |
NCBI GenInfo Identifier: | 12229745 |
NCBI Gene ID: | 9391 |
NCBI Accession: | O76071.1 |
UniProt Secondary Accession: | O76071,Q53FM5, A0MNN9, |
UniProt Related Accession: | O76071 |
Molecular Weight: | 339 |
NCBI Full Name: | Probable cytosolic iron-sulfur protein assembly protein CIAO1 |
NCBI Synonym Full Names: | cytosolic iron-sulfur assembly component 1 |
NCBI Official Symbol: | CIAO1 |
NCBI Official Synonym Symbols: | CIA1; WDR39 |
NCBI Protein Information: | probable cytosolic iron-sulfur protein assembly protein CIAO1; WD40 protein Ciao1; WD repeat domain 39; WD repeat-containing protein 39; cytosolic iron-sulfur protein assembly 1 homolog |
UniProt Protein Name: | Probable cytosolic iron-sulfur protein assembly protein CIAO1 |
UniProt Synonym Protein Names: | WD repeat-containing protein 39 |
Protein Family: | Probable cytosolic iron-sulfur protein assembly protein |
UniProt Gene Name: | CIAO1 |
UniProt Entry Name: | CIAO1_HUMAN |