CD300A Antibody (PACO45339)
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주문- SKU:
- PACO45339
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | CD300A Antibody (PACO45339) |
Antibody SKU: | PACO45339 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human CMRF35-like molecule 8 protein (18-180AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: CNTN4 antibody IgG at 2.22µg/ml + Mouse kidney tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 34, 21, 12, 17 kDa. Observed band size: 34 kDa.. | |
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO45339 at dilution of 1:100. |
Background: | Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. |
Synonyms: | CMRF35-like molecule 8 (CLM-8) (CD300 antigen-like family member A) (CMRF-35-H9) (CMRF35-H9) (CMRF35-H) (IRC1/IRC2) (Immunoglobulin superfamily member 12) (IgSF12) (Inhibitory receptor protein 60) (IRp60) (NK inhibitory receptor) (CD antigen CD300a), CD300A, CMRF35H IGSF12 |
UniProt Protein Function: | MAIR-I: Inhibitory receptor which may contribute to the down- regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Belongs to the CD300 family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Immunoglobulin superfamily; Membrane protein, integral Chromosomal Location of Human Ortholog: 17q25.1 Cellular Component: membrane; plasma membrane Molecular Function:phosphatidylethanolamine binding; phosphatidylserine binding; protein binding Biological Process: negative regulation of B cell proliferation; negative regulation of B cell receptor signaling pathway; negative regulation of fibroblast proliferation; negative regulation of MAP kinase activity; negative regulation of mast cell activation during immune response; negative regulation of mast cell degranulation; negative regulation of MyD88-dependent toll-like receptor signaling pathway; negative regulation of NK T cell activation; negative regulation of phagocytosis, engulfment; neutrophil degranulation; positive regulation of phosphoprotein phosphatase activity; regulation of immune response; regulation of T cell receptor signaling pathway |
NCBI Summary: | This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. This gene is located on chromosome 17 in a cluster with all but one of the other family members. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] |
UniProt Code: | Q9UGN4 |
NCBI GenInfo Identifier: | 126302534 |
NCBI Gene ID: | 11314 |
NCBI Accession: | Q9UGN4.2 |
UniProt Secondary Accession: | Q9UGN4,O95100, Q9HD97, Q9P0F3, Q9UBK4, Q9UMS9, Q9UMT0 A8MW96, |
UniProt Related Accession: | Q9UGN4 |
Molecular Weight: | 33kDa |
NCBI Full Name: | CMRF35-like molecule 8 |
NCBI Synonym Full Names: | CD300a molecule |
NCBI Official Symbol: | CD300A |
NCBI Official Synonym Symbols: | IRC1; IRC2; CLM-8; IRp60; IGSF12; CMRF35H; CMRF-35H; CMRF35-H; CMRF35H9; CMRF35-H9; IRC1/IRC2; CMRF-35-H9 |
NCBI Protein Information: | CMRF35-like molecule 8 |
UniProt Protein Name: | CMRF35-like molecule 8 |
UniProt Synonym Protein Names: | CD300 antigen-like family member A; CMRF-35-H9; CMRF35-H9; CMRF35-H; IRC1/IRC2; Immunoglobulin superfamily member 12; IgSF12; Inhibitory receptor protein 60; IRp60; NK inhibitory receptor; CD_antigen: CD300a |
Protein Family: | CMRF35-like molecule |
UniProt Gene Name: | CD300A |
Antibodies |
Anti-CD300A Antibody (CAB10006) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |