ATG14 Antibody (PACO13377)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO13377
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ATG14 Antibody (PACO13377) |
Antibody SKU: | PACO13377 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human Barkor-Specific |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | KIAA0831;KIAA0831;ATG14;MGC126291;MGC126292 ; |
UniProt Protein Function: | Barkor: Required for both basal and inducible autophagy. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner. Forms a complex with BECN1, PIK3C3 and PIK3R4, but not with UVRAG, nor with KIAA0226/Rubicon. UVRAG and ATG14/Barkor form mutually exclusive complexes with BECN1 through direct competition. The complex containing ATG14 up-regulates autophagy, while the one containing Rubicon down-regulates autophagy. Interacts with PIK3CB. Belongs to the Barkor family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Autophagy Chromosomal Location of Human Ortholog: 14q22.3 Cellular Component: autophagic vacuole; axoneme; cytoplasm; cytosol; endoplasmic reticulum membrane; nucleus; pre-autophagosomal structure membrane Molecular Function:protein binding Biological Process: autophagic vacuole formation; cellular response to glucose starvation; cellular response to starvation; endosome to lysosome transport; macroautophagy; negative regulation of protein amino acid phosphorylation; positive regulation of phosphoinositide 3-kinase activity; positive regulation of protein amino acid phosphorylation; regulation of protein amino acid phosphorylation |
UniProt Code: | Q6ZNE5 |
NCBI GenInfo Identifier: | 67461020 |
NCBI Gene ID: | 22863 |
NCBI Accession: | Q6ZNE5.1 |
UniProt Secondary Accession: | Q6ZNE5,O94920, Q32MK7, Q32MK8, A6NJE4, A8K9U5, B7ZWP5 |
UniProt Related Accession: | Q6ZNE5 |
Molecular Weight: | 42,434 Da |
NCBI Full Name: | Beclin 1-associated autophagy-related key regulator |
NCBI Synonym Full Names: | autophagy related 14 |
NCBI Official Symbol: | ATG14 |
NCBI Official Synonym Symbols: | ATG14L; BARKOR; KIAA0831 |
NCBI Protein Information: | beclin 1-associated autophagy-related key regulator |
UniProt Protein Name: | Beclin 1-associated autophagy-related key regulator |
UniProt Synonym Protein Names: | Autophagy-related protein 14-like protein |
Protein Family: | Autophagy-related protein |
UniProt Gene Name: | ATG14 |
UniProt Entry Name: | BAKOR_HUMAN |