Anti-UQCRC2 Antibody (RACO0384)
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주문- SKU:
- RACO0384
- Product type:
- Recombinant Antibody
- Reactivity:
- Human
- Host Species:
- Human
- Isotype:
- IgG
- Application:
- WB
- Application:
- ELISA
- Application:
- IHC
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Product Name: | UQCRC2 Antibody |
Product SKU: | RACO0384 |
Size: | 50ul |
Host Species: | Homo sapiens (Human) |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | WB:1:500-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | A synthesized peptide derived from human UQCRC2 |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | Affinity-chromatography |
Clonality: | Monoclonal |
Isotype: | Rabbit IgG |
Conjugate: | Non-conjugated |
Background: | This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex. |
Synonyms: | Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome-c reductase complex core protein 2), UQCRC2 |
IHC image of RACO0384 diluted at 1:100 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. | |
IHC image of RACO0384 diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. | |
Western Blot. Positive WB detected in HepG2 whole cell lysate 293 whole cell lysate U251 whole cell lysate MCF-7 whole cell lysate All lanes UQCRC2 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1:50000 dilution. Predicted band size: 49 kDa. Observed band size: 49 kDa. |
UniProt Protein Function: | UQCRC2: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex. Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily. |
UniProt Protein Details: | Protein type:EC 1.10.2.2; Mitochondrial; Oxidoreductase; Energy Metabolism - oxidative phosphorylation Chromosomal Location of Human Ortholog: 16p12 Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex III Molecular Function:protein binding; metal ion binding; metalloendopeptidase activity; protein complex binding Biological Process: cellular metabolic process; aerobic respiration; proteolysis; oxidative phosphorylation Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 5 |
NCBI Summary: | The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5. [provided by RefSeq, Jul 2015] |
UniProt Code: | P22695 |
NCBI GenInfo Identifier: | 21903482 |
NCBI Gene ID: | 7385 |
NCBI Accession: | P22695.3 |
UniProt Secondary Accession: | P22695,Q9DB77, P32551, |
UniProt Related Accession: | P22695 |
Molecular Weight: | 48kDa |
NCBI Full Name: | Cytochrome b-c1 complex subunit 2, mitochondrial |
NCBI Synonym Full Names: | ubiquinol-cytochrome c reductase core protein 2 |
NCBI Official Symbol: | UQCRC2Â Â |
NCBI Official Synonym Symbols: | QCR2; UQCR2; MC3DN5Â Â |
NCBI Protein Information: | cytochrome b-c1 complex subunit 2, mitochondrial |
UniProt Protein Name: | Cytochrome b-c1 complex subunit 2, mitochondrial |
UniProt Synonym Protein Names: | Complex III subunit 2; Core protein II; Ubiquinol-cytochrome-c reductase complex core protein 2 |
UniProt Gene Name: | UQCRC2Â Â |
UniProt Entry Name: | QCR2_HUMAN |