UQCRC2 Antibody (PACO17390)
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주문- SKU:
- PACO17390
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | UQCRC2 Antibody (PACO17390) |
Antibody SKU: | PACO17390 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human UQCRC2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO17390(UQCRC2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Jurkat, Raji, hepg2, A431 and HT-29 cell, Primary antibody: PACO17390(UQCRC2 Antibody) at dilution 1/400 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO17390(UQCRC2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex. |
Synonyms: | ubiquinol-cytochrome c reductase core protein II |
UniProt Protein Function: | UQCRC2: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex. Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily. |
UniProt Protein Details: | Protein type:EC 1.10.2.2; Mitochondrial; Oxidoreductase; Energy Metabolism - oxidative phosphorylation Chromosomal Location of Human Ortholog: 16p12 Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex III Molecular Function:protein binding; metal ion binding; metalloendopeptidase activity; protein complex binding Biological Process: cellular metabolic process; aerobic respiration; proteolysis; oxidative phosphorylation Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 5 |
NCBI Summary: | The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5. [provided by RefSeq, Jul 2015] |
UniProt Code: | P22695 |
NCBI GenInfo Identifier: | 21903482 |
NCBI Gene ID: | 7385 |
NCBI Accession: | P22695.3 |
UniProt Secondary Accession: | P22695,Q9DB77, P32551, |
UniProt Related Accession: | P22695 |
Molecular Weight: | 48kDa |
NCBI Full Name: | Cytochrome b-c1 complex subunit 2, mitochondrial |
NCBI Synonym Full Names: | ubiquinol-cytochrome c reductase core protein 2 |
NCBI Official Symbol: | UQCRC2 |
NCBI Official Synonym Symbols: | QCR2; UQCR2; MC3DN5 |
NCBI Protein Information: | cytochrome b-c1 complex subunit 2, mitochondrial |
UniProt Protein Name: | Cytochrome b-c1 complex subunit 2, mitochondrial |
UniProt Synonym Protein Names: | Complex III subunit 2; Core protein II; Ubiquinol-cytochrome-c reductase complex core protein 2 |
UniProt Gene Name: | UQCRC2 |
UniProt Entry Name: | QCR2_HUMAN |