Anti-TBK1 Antibody (CAB14641)
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주문- SKU:
- CAB14641
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
Antibody Name: | Anti-TBK1 Antibody |
Antibody SKU: | CAB14641 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IF |
Reactivity: | Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of mouse TBK1 (NP_062760.3). |
Application: | WB IF |
Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
Reactivity: | Mouse, Rat |
Positive Samples: |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of mouse TBK1 (NP_062760.3). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | EPSN AYGL PESE FLIV LRDV VGGM NHLR ENGI VHRD IKPG NIMR VIGE DGQS VYKL TDFG AARE LEDD EQFV SLYG TEEY LHPD MYER AVLR KDHQ KKYG A |
Gene ID: | 56480 |
Uniprot: | |
Cellular Location: | Cytoplasm |
Calculated MW: | 83kDa |
Observed MW: | Refer to figures |
Synonyms: | 1200008B05Rik, AI462036, AW048562, TBK1, FTDALS4, NAK, T2K |
Background: | The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. |