AKR1B1 Antibody (PACO47294)
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주문- SKU:
- PACO47294
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | AKR1B1 Antibody (PACO47294) |
Antibody SKU: | PACO47294 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Aldose reductase protein (114-230AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Hela whole cell lysate. All lanes: AKR1B1 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 36 kDa. Observed band size: 36, 50 kDa.. | |
Immunofluorescent analysis of A549 cells using PACO47294 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human liver tissue using PACO47294 at dilution of 1:100. |
Background: | Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. |
Synonyms: | Aldose reductase (AR) (EC 1.1.1.21) (Aldehyde reductase) (Aldo-keto reductase family 1 member B1), AKR1B1, ALDR1 |
UniProt Protein Function: | Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. |
NCBI Summary: | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009] |
UniProt Code: | P15121 |
NCBI GenInfo Identifier: | 113596 |
NCBI Gene ID: | 231 |
NCBI Accession: | P15121.3 |
UniProt Secondary Accession: | P15121,Q5U031, Q6FGA4, Q6ICP2, Q9BS21, Q9UCI9, B2R8N3 |
UniProt Related Accession: | P15121 |
Molecular Weight: | |
NCBI Full Name: | Aldose reductase |
NCBI Synonym Full Names: | aldo-keto reductase family 1 member B |
NCBI Official Symbol: | AKR1B1 |
NCBI Official Synonym Symbols: | AR; ADR; ALR2; ALDR1 |
NCBI Protein Information: | aldose reductase |
UniProt Protein Name: | Aldose reductase |
UniProt Synonym Protein Names: | Aldehyde reductase; Aldo-keto reductase family 1 member B1 |
Protein Family: | Aldose reductase |
UniProt Gene Name: | AKR1B1 |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |