AKR1B1 Antibody (PACO13830)
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주문- SKU:
- PACO13830
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | AKR1B1 Antibody (PACO13830) |
Antibody SKU: | PACO13830 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human AKR1B1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela cells, 293T cells, Primary antibody: PACO13830(AKR1B1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO13830(AKR1B1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. |
Synonyms: | aldo-keto reductase family 1, member B1 (aldose reductase) |
UniProt Protein Function: | Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. |
NCBI Summary: | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009] |
UniProt Code: | P15121 |
NCBI GenInfo Identifier: | 113596 |
NCBI Gene ID: | 231 |
NCBI Accession: | P15121.3 |
UniProt Secondary Accession: | P15121,Q5U031, Q6FGA4, Q6ICP2, Q9BS21, Q9UCI9, B2R8N3 |
UniProt Related Accession: | P15121 |
Molecular Weight: | |
NCBI Full Name: | Aldose reductase |
NCBI Synonym Full Names: | aldo-keto reductase family 1 member B |
NCBI Official Symbol: | AKR1B1 |
NCBI Official Synonym Symbols: | AR; ADR; ALR2; ALDR1 |
NCBI Protein Information: | aldose reductase |
UniProt Protein Name: | Aldose reductase |
UniProt Synonym Protein Names: | Aldehyde reductase; Aldo-keto reductase family 1 member B1 |
Protein Family: | Aldose reductase |
UniProt Gene Name: | AKR1B1 |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |