ABCC4 Antibody (PACO49366)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO49366
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ABCC4 Antibody (PACO49366) |
Antibody SKU: | PACO49366 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Multidrug resistance-associated protein 4 protein (562-697AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunofluorescent analysis of HepG2 cells using PACO49366 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | May be an organic anion pump relevant to cellular detoxification. |
Synonyms: | Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B), ABCC4, MRP4 |
UniProt Protein Function: | ABCC4: a widely-expressed multi-pass membrane protein. An organic anion pump involved in cellular detoxification. Widely expressed, with particularly high levels in prostate, but is barely detectable in liver. |
UniProt Protein Details: | Protein type:Transporter; Membrane protein, multi-pass; Transporter, ABC family; Membrane protein, integral Chromosomal Location of Human Ortholog: 13q32 Cellular Component: membrane; basolateral plasma membrane; integral to membrane; plasma membrane; platelet dense granule membrane Molecular Function:ATPase activity, coupled to transmembrane movement of substances; 15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ATP binding Biological Process: response to drug; platelet activation; platelet degranulation; positive regulation of smooth muscle cell proliferation; response to organic nitrogen; blood coagulation; transmembrane transport; response to organic cyclic substance |
NCBI Summary: | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
UniProt Code: | O15439 |
NCBI GenInfo Identifier: | 206729914 |
NCBI Gene ID: | 10257 |
NCBI Accession: | O15439.3 |
UniProt Related Accession: | O15439 |
Molecular Weight: | |
NCBI Full Name: | Multidrug resistance-associated protein 4 |
NCBI Synonym Full Names: | ATP binding cassette subfamily C member 4 |
NCBI Official Symbol: | ABCC4 |
NCBI Official Synonym Symbols: | MRP4; MOATB; MOAT-B |
NCBI Protein Information: | multidrug resistance-associated protein 4 |
UniProt Protein Name: | Multidrug resistance-associated protein 4 |
UniProt Synonym Protein Names: | ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B |
Protein Family: | ABC transporter C family |
UniProt Gene Name: | ABCC4 |
UniProt Entry Name: | MRP4_HUMAN |
Antibodies | ELISA Kits |
Anti-MRP4 / ABCC4 Antibody (CAB2198) | Human ABCC4 / MRP4 ELISA Kit |
Human Multidrug resistance-associated protein 4 (ABCC4) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |