YWHAQ Antibody (PACO18272)
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주문- SKU:
- PACO18272
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | YWHAQ Antibody (PACO18272) |
Antibody SKU: | PACO18272 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human YWHAQ |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18272(YWHAQ Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 10+12%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Mouse brain tissue, A549 cells, human lymphoma tissue, NIH/3T3 cells, human colon cancer tissue, Primary antibody: PACO18272(YWHAQ Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO18272(YWHAQ Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. |
Synonyms: | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide |
UniProt Protein Function: | 14-3-3 theta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Associates with c-BCR and BCR-Abl. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 2p25.1 Cellular Component: cytoplasm; cytoplasmic vesicle membrane; cytosol; focal adhesion; membrane; mitochondrion; protein complex Molecular Function:protein binding; protein C-terminus binding; protein domain specific binding; protein N-terminus binding Biological Process: apoptosis; gene expression; negative regulation of transcription, DNA-dependent; programmed cell death; small GTPase mediated signal transduction; substantia nigra development; transcription initiation from RNA polymerase II promoter |
NCBI Summary: | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008] |
UniProt Code: | P27348 |
NCBI GenInfo Identifier: | 112690 |
NCBI Gene ID: | 10971 |
NCBI Accession: | P27348.1 |
UniProt Secondary Accession: | P27348,Q567U5, Q5TZU8, Q9UP48, D6W4Z5, |
UniProt Related Accession: | P27348 |
Molecular Weight: | |
NCBI Full Name: | 14-3-3 protein theta |
NCBI Synonym Full Names: | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta |
NCBI Official Symbol: | YWHAQ |
NCBI Official Synonym Symbols: | 1C5; HS1; 14-3-3 |
NCBI Protein Information: | 14-3-3 protein theta |
UniProt Protein Name: | 14-3-3 protein theta |
UniProt Synonym Protein Names: | 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1 |
Protein Family: | 14-3-3 protein |
UniProt Gene Name: | YWHAQ |
UniProt Entry Name: | 1433T_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |