WHSC1L1 Antibody (PACO13241)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO13241
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | WHSC1L1 Antibody (PACO13241) |
Antibody SKU: | PACO13241 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human WHSC1L1 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | Wolf-Hirschhorn syndrome candidate 1-like 1;WHSC1L1;DKFZp667H044;FLJ20353;MGC126766;MGC142029;NSD3;pp14328 ; |
UniProt Protein Function: | WHSC1L1: is related to the Wolf-Hirschhorn syndrome candidate-1 protein containing PWWP (proline-tryptophan-tryptophan-proline) domains. The function of the protein has not been determined. Two alternatively spliced isoforms have been described. |
UniProt Protein Details: | Protein type:Amino Acid Metabolism - lysine degradation; Methyltransferase, protein lysine; Oncoprotein; Histone-binding; EC 2.1.1.43; Methyltransferase Chromosomal Location of Human Ortholog: 8p11.2 Cellular Component: nucleoplasm; chromosome; nucleus Molecular Function:protein binding; zinc ion binding; histone lysine N-methyltransferase activity (H3-K4 specific); histone-lysine N-methyltransferase activity; histone lysine N-methyltransferase activity (H3-K27 specific) Biological Process: histone methylation; establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; histone H3-K4 methylation; negative regulation of transcription, DNA-dependent Disease: Leukemia, Acute Myeloid |
NCBI Summary: | This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described. [provided by RefSeq, May 2015] |
UniProt Code: | Q9BZ95 |
NCBI GenInfo Identifier: | 74761342 |
NCBI Gene ID: | 54904 |
NCBI Accession: | Q9BZ95.1 |
UniProt Secondary Accession: | Q9BZ95,Q6P2L6, |
UniProt Related Accession: | Q9BZ95 |
Molecular Weight: | 162kDa |
NCBI Full Name: | Histone-lysine N-methyltransferase NSD3 |
NCBI Synonym Full Names: | nuclear receptor binding SET domain protein 3 |
NCBI Official Symbol: | NSD3 |
NCBI Official Synonym Symbols: | KMT3F; KMT3G; WHISTLE; WHSC1L1; pp14328 |
NCBI Protein Information: | histone-lysine N-methyltransferase NSD3 |
UniProt Protein Name: | Histone-lysine N-methyltransferase NSD3 |
UniProt Synonym Protein Names: | Nuclear SET domain-containing protein 3; Protein whistle; WHSC1-like 1 isoform 9 with methyltransferase activity to lysine; Wolf-Hirschhorn syndrome candidate 1-like protein 1; WHSC1-like protein 1 |
UniProt Gene Name: | WHSC1L1 |
UniProt Entry Name: | NSD3_HUMAN |