WDR18 Antibody (PACO41538)
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주문- SKU:
- PACO41538
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | WDR18 Antibody (PACO41538) |
Antibody SKU: | PACO41538 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Recombinant Human WD repeat-containing protein 18 protein (231-432AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | May play a role during development (By similarity). Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. |
Synonyms: | WD repeat-containing protein 18, WDR18 |
UniProt Protein Function: | WDR18: a WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: nucleoplasm Molecular Function:protein binding Biological Process: rRNA processing |
NCBI Summary: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9BV38 |
NCBI GenInfo Identifier: | 37589023 |
NCBI Gene ID: | 57418 |
NCBI Accession: | BC001648 |
UniProt Secondary Accession: | Q9BV38,O60390, Q9BWR2, |
UniProt Related Accession: | Q9BV38 |
Molecular Weight: | 47,405 Da |
NCBI Full Name: | Homo sapiens WD repeat domain 18, mRNA |
NCBI Synonym Full Names: | WD repeat domain 18 |
NCBI Official Symbol: | WDR18 |
NCBI Official Synonym Symbols: | Ipi3; R32184_1 |
NCBI Protein Information: | WD repeat-containing protein 18 |
UniProt Protein Name: | WD repeat-containing protein 18 |
Protein Family: | WD repeat-containing protein |
UniProt Gene Name: | WDR18 |
UniProt Entry Name: | WDR18_HUMAN |