VEGFB Antibody (PACO06852)
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주문- SKU:
- PACO06852
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | VEGFB Antibody (PACO06852) |
Antibody SKU: | PACO06852 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:20000, WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from the Internal region of human VEGF-B. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot analysis of COLO 293T HELA cells using VEGF-B Polyclonal Antibody. | |
Western Blot analysis of Jurkat cells using VEGF-B Polyclonal Antibody. |
Synonyms: | VEGFB; VRF; Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VRF |
UniProt Protein Function: | VEGFB: Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. Homodimer; disulfide-linked. Can also form heterodimer with VEGF. Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas. Belongs to the PDGF/VEGF growth factor family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted; Cell cycle regulation; Motility/polarity/chemotaxis; Cytokine Chromosomal Location of Human Ortholog: 11q13 Cellular Component: extracellular region Molecular Function:protein binding Biological Process: platelet degranulation; vascular endothelial growth factor receptor signaling pathway |
NCBI Summary: | This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011] |
UniProt Code: | P49765 |
NCBI GenInfo Identifier: | 17380554 |
NCBI Gene ID: | 7423 |
NCBI Accession: | P49765.2 |
UniProt Secondary Accession: | P49765,Q16528, |
UniProt Related Accession: | P49765 |
Molecular Weight: | 21,261 Da |
NCBI Full Name: | Vascular endothelial growth factor B |
NCBI Synonym Full Names: | vascular endothelial growth factor B |
NCBI Official Symbol: | VEGFB |
NCBI Official Synonym Symbols: | VRF; VEGFL |
NCBI Protein Information: | vascular endothelial growth factor B |
UniProt Protein Name: | Vascular endothelial growth factor B |
UniProt Synonym Protein Names: | VEGF-related factor; VRF |
Protein Family: | Vascular endothelial growth factor |
UniProt Gene Name: | VEGFB |
UniProt Entry Name: | VEGFB_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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