USP44 Antibody (PACO06991)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO06991
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | USP44 Antibody (PACO06991) |
Antibody SKU: | PACO06991 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:40000, WB:1:500-1:2000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from the Internal region of human USP44. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of mouse-kidney lysis using USP44 antibody. | |
Western Blot analysis of 293T cells using USP44 Polyclonal Antibody. |
Synonyms: | USP44; Ubiquitin carboxyl-terminal hydrolase 44; Deubiquitinating enzyme 44; Ubiquitin thioesterase 44; Ubiquitin-specific-processing protease 44 |
UniProt Protein Function: | USP44: Deubiquitinase that plays a key role in the spindle checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome (APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20- APC/C ternary complex (also named mitotic checkpoint), thereby preventing premature activation of the APC/C. Belongs to the peptidase C19 family. USP44 subfamily. |
UniProt Protein Details: | Protein type:Protease; EC 3.4.19.12; Ubiquitin-specific protease Chromosomal Location of Human Ortholog: 12q22 Cellular Component: microtubule cytoskeleton; nucleolus; nucleus Molecular Function:protein binding; ubiquitin-specific protease activity; zinc ion binding Biological Process: cell division; mitosis; proteasomal ubiquitin-dependent protein catabolic process; protein deubiquitination |
NCBI Summary: | Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP44 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9H0E7 |
NCBI GenInfo Identifier: | 300669621 |
NCBI Gene ID: | 84101 |
NCBI Accession: | Q9H0E7.2 |
UniProt Secondary Accession: | Q9H0E7,B2RDW3, |
UniProt Related Accession: | Q9H0E7 |
Molecular Weight: | 81,185 Da |
NCBI Full Name: | Ubiquitin carboxyl-terminal hydrolase 44 |
NCBI Synonym Full Names: | ubiquitin specific peptidase 44 |
NCBI Official Symbol: | USP44 |
NCBI Protein Information: | ubiquitin carboxyl-terminal hydrolase 44 |
UniProt Protein Name: | Ubiquitin carboxyl-terminal hydrolase 44 |
UniProt Synonym Protein Names: | Deubiquitinating enzyme 44; Ubiquitin thioesterase 44; Ubiquitin-specific-processing protease 44 |
Protein Family: | Ubiquitin carboxyl-terminal hydrolase |
UniProt Gene Name: | USP44 |
UniProt Entry Name: | UBP44_HUMAN |
Antibodies |
Anti-USP44 Antibody (CAB15528) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |