USP16 Antibody (PACO02340)
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주문- SKU:
- PACO02340
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | USP16 Antibody |
Antibody SKU: | PACO02340 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from the Internal region of human USP16. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | USP16; MSTP039; Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme 16; Ubiquitin thioesterase 16; Ubiquitin-processing protease UBP-M; Ubiquitin-specific-processing protease 16 |
UniProt Protein Function: | USP16: a ubiquitous ubiquitin-processing protease that may de-ubiquitinate one or more critical proteins that are involved in the condensation of mitotic chromosomes, possibly acting selectively on histones H2A and H2B, the major ubiquitinated proteins of chromatin. Is phosphorylated at the onset of mitosis and dephosphorylated during the metaphase/anaphase transition. |
UniProt Protein Details: | Protein type:Protease; Ubiquitin conjugating system; EC 3.4.19.12; Ubiquitin-specific protease Chromosomal Location of Human Ortholog: 21q22.11 Cellular Component: cytoplasm; nucleus Molecular Function:cysteine-type endopeptidase activity; histone binding; transcription coactivator activity; ubiquitin binding; ubiquitin-specific protease activity; zinc ion binding Biological Process: cell cycle; histone deubiquitination; mitosis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of translational elongation; protein homotetramerization; regulation of transcription from RNA polymerase II promoter; response to DNA damage stimulus |
NCBI Summary: | This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y5T5 |
NCBI GenInfo Identifier: | 6686071 |
NCBI Gene ID: | 10600 |
NCBI Accession: | Q9Y5T5.1 |
UniProt Secondary Accession: | Q9Y5T5,Q53GP7, Q53HA0, Q5VKN8, Q8NEL3, Q9H3E6, A8MU43 B3KN13, B4DFV8, B4DY37, D3DSD9, |
UniProt Related Accession: | Q9Y5T5 |
Molecular Weight: | 46,599 Da |
NCBI Full Name: | Ubiquitin carboxyl-terminal hydrolase 16 |
NCBI Synonym Full Names: | ubiquitin specific peptidase 16 |
NCBI Official Symbol: | USP16 |
NCBI Official Synonym Symbols: | UBPM; UBP-M |
NCBI Protein Information: | ubiquitin carboxyl-terminal hydrolase 16 |
UniProt Protein Name: | Ubiquitin carboxyl-terminal hydrolase 16 |
UniProt Synonym Protein Names: | Deubiquitinating enzyme 16 |
UniProt Gene Name: | USP16 |
UniProt Entry Name: | UBP16_HUMAN |