UQCC2 Antibody (PACO45123)
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주문- SKU:
- PACO45123
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | UQCC2 Antibody (PACO45123) |
Antibody SKU: | PACO45123 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Ubiquinol-cytochrome-c reductase complex assembly factor 2 protein (14-126AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: UQCC2 antibody at 3.35 µg/ml. Lane 1: HepG2 whole cell lysate. Lane 2: 293T whole cell lysate. Lane 3: Jurkat whole cell lysate. Lane 4: A431 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 15 kDa. Observed band size: 15, 40, 80 kDa.. | |
Immunohistochemistry of paraffin-embedded human liver tissue using PACO45123 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human heart tissue using PACO45123 at dilution of 1:100. |
Background: | Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex). Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells. Involved in cytochrome b translation and/or stability. |
Synonyms: | Ubiquinol-cytochrome-c reductase complex assembly factor 2 (Breast cancer-associated protein SGA-81M) (Mitochondrial nucleoid factor 1) (Mitochondrial protein M19), UQCC2, C6orf125 MNF1 |
UniProt Protein Function: | UQCC2: Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells |
UniProt Protein Details: | Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 6p21.31 Cellular Component: mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial matrix; mitochondrion; nuclear body Molecular Function:protein binding Biological Process: regulation of insulin secretion; regulation of oxidative phosphorylation Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 7 |
NCBI Summary: | This gene encodes a nucleoid protein localized to the mitochondria inner membrane. The encoded protein affects regulation of insulin secretion, mitochondrial ATP production, and myogenesis through modulation of mitochondrial respiratory chain activity. [provided by RefSeq, Oct 2012] |
UniProt Code: | Q9BRT2 |
NCBI GenInfo Identifier: | 73917719 |
NCBI Gene ID: | 84300 |
NCBI Accession: | Q9BRT2.1 |
UniProt Secondary Accession: | Q9BRT2,B2R4I0, |
UniProt Related Accession: | Q9BRT2 |
Molecular Weight: | 15kDa |
NCBI Full Name: | Ubiquinol-cytochrome-c reductase complex assembly factor 2 |
NCBI Synonym Full Names: | ubiquinol-cytochrome c reductase complex assembly factor 2 |
NCBI Official Symbol: | UQCC2 |
NCBI Official Synonym Symbols: | M19; Cbp6; MNF1; C6orf125; C6orf126; bA6B20.2 |
NCBI Protein Information: | ubiquinol-cytochrome-c reductase complex assembly factor 2 |
UniProt Protein Name: | Ubiquinol-cytochrome-c reductase complex assembly factor 2 |
UniProt Synonym Protein Names: | Breast cancer-associated protein SGA-81M; Mitochondrial nucleoid factor 1; Mitochondrial protein M19 |
Protein Family: | Ubiquinol-cytochrome-c reductase complex assembly factor |
UniProt Gene Name: | UQCC2 |