UBE2G2 Antibody (PACO13030)
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주문- SKU:
- PACO13030
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | UBE2G2 Antibody (PACO13030) |
Antibody SKU: | PACO13030 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human UBE2G2 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast);UBE2G2;UBC7 ; |
UniProt Protein Function: | UBE2G2: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Involved in endoplasmic reticulum- associated degradation (ERAD). Belongs to the ubiquitin-conjugating enzyme family. |
UniProt Protein Details: | Protein type:EC 6.3.2.19; Endoplasmic reticulum; Ligase; Ubiquitin conjugating system; Ubiquitin ligase Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: cytosol Molecular Function:protein binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity Biological Process: cellular protein catabolic process; ER-associated protein catabolic process; protein amino acid N-linked glycosylation via asparagine; protein ubiquitination; ubiquitin-dependent protein catabolic process |
NCBI Summary: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011] |
UniProt Code: | P60604 |
NCBI GenInfo Identifier: | 45593583 |
NCBI Gene ID: | 7327 |
NCBI Accession: | P60604.1 |
UniProt Secondary Accession: | P60604,P56554, A6NMQ7, A8K3L4, D3DSL7, |
UniProt Related Accession: | P60604 |
Molecular Weight: | 19kDa |
NCBI Full Name: | Ubiquitin-conjugating enzyme E2 G2 |
NCBI Synonym Full Names: | ubiquitin conjugating enzyme E2 G2 |
NCBI Official Symbol: | UBE2G2 |
NCBI Official Synonym Symbols: | UBC7 |
NCBI Protein Information: | ubiquitin-conjugating enzyme E2 G2 |
UniProt Protein Name: | Ubiquitin-conjugating enzyme E2 G2 |
UniProt Synonym Protein Names: | E2 ubiquitin-conjugating enzyme G2; Ubiquitin carrier protein G2; Ubiquitin-protein ligase G2 |
Protein Family: | Ubiquitin-conjugating enzyme |
UniProt Gene Name: | UBE2G2 |