UBA2 Antibody (PACO13010)
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주문- SKU:
- PACO13010
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | UBA2 Antibody (PACO13010) |
Antibody SKU: | PACO13010 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse |
Immunogen: | Human UBA2 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | ubiquitin-like modifier activating enzyme 2;UBA2;ARX;FLJ13058;HRIHFB2115;SAE2 ; |
UniProt Protein Function: | SAE2: a protein of the ubiquitin-activating E1 family. Acts as a UBL1 E1 ligase. Mediates ATP-dependent activation of UBL1 and formation of a thiolester with a conserved cysteine residue on SAE2. |
UniProt Protein Details: | Protein type:Ubiquitin ligase; Motility/polarity/chemotaxis; EC 6.3.2.-; EC 6.3.2.19; Ubiquitin conjugating system; Ligase Chromosomal Location of Human Ortholog: 19q12 Cellular Component: nucleoplasm; cytosol; nucleus Molecular Function:SUMO activating enzyme activity; protein binding; protein heterodimerization activity; metal ion binding; enzyme activator activity; transcription factor binding; ATP binding Biological Process: positive regulation of catalytic activity; cellular protein metabolic process; protein sumoylation; SMT3-dependent protein catabolic process; post-translational protein modification |
NCBI Summary: | Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010] |
UniProt Code: | Q9UBT2 |
NCBI GenInfo Identifier: | 42559898 |
NCBI Gene ID: | 10054 |
NCBI Accession: | Q9UBT2.2 |
UniProt Secondary Accession: | Q9UBT2,O95605, Q59H87, Q6IBP6, Q9NTJ1, Q9UED2, B3KWB9 |
UniProt Related Accession: | Q9UBT2 |
Molecular Weight: | 640 |
NCBI Full Name: | SUMO-activating enzyme subunit 2 |
NCBI Synonym Full Names: | ubiquitin-like modifier activating enzyme 2 |
NCBI Official Symbol: | UBA2 |
NCBI Official Synonym Symbols: | ARX; SAE2; HRIHFB2115 |
NCBI Protein Information: | SUMO-activating enzyme subunit 2; SUMO1 activating enzyme subunit 2; SUMO-1 activating enzyme subunit 2; ubiquitin-like 1-activating enzyme E1B; anthracycline-associated resistance ARX; ubiquitin-like modifier-activating enzyme 2; UBA2, ubiquitin-activating enzyme E1 homolog |
UniProt Protein Name: | SUMO-activating enzyme subunit 2 |
UniProt Synonym Protein Names: | Anthracycline-associated resistance ARX; Ubiquitin-like 1-activating enzyme E1B; Ubiquitin-like modifier-activating enzyme 2 |
Protein Family: | Ubiquitin-activating enzyme |
UniProt Gene Name: | UBA2 |
UniProt Entry Name: | SAE2_HUMAN |