TYMP Antibody (PACO02099)
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주문- SKU:
- PACO02099
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TYMP Antibody |
Antibody SKU: | PACO02099 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human |
Immunogen: | synthesized peptide derived from the N-terminal region of human PD-ECGF. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | TYMP; ECGF1; Thymidine phosphorylase; TP; Gliostatin; Platelet-derived endothelial cell growth factor; PD-ECGF; TdRPase |
UniProt Protein Function: | ECGF1: May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro. Homodimer. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Nucleotide Metabolism - pyrimidine; EC 2.4.2.4; Phosphorylase; DNA replication; Transferase; Cytokine; Xenobiotic Metabolism - drug metabolism - other enzymes Chromosomal Location of Human Ortholog: 22q13.33 Cellular Component: cytosol Molecular Function:phosphorylase activity; platelet-derived growth factor receptor binding; transferase activity, transferring pentosyl groups Biological Process: DNA replication; mitochondrial genome maintenance; pyrimidine nucleoside catabolic process; pyrimidine nucleoside salvage; pyrimidine nucleotide metabolic process Disease: Mitochondrial Dna Depletion Syndrome 1 (mngie Type) |
NCBI Summary: | This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012] |
UniProt Code: | P19971 |
NCBI GenInfo Identifier: | 67477361 |
NCBI Gene ID: | 1890 |
NCBI Accession: | P19971.2 |
UniProt Secondary Accession: | P19971,Q13390, Q8WVB7, A8MW15, H9KVA0, |
UniProt Related Accession: | P19971 |
Molecular Weight: | 50,405 Da |
NCBI Full Name: | Thymidine phosphorylase |
NCBI Synonym Full Names: | thymidine phosphorylase |
NCBI Official Symbol: | TYMP |
NCBI Official Synonym Symbols: | TP; ECGF; ECGF1; MNGIE; MEDPS1; MTDPS1; PDECGF; hPD-ECGF |
NCBI Protein Information: | thymidine phosphorylase |
UniProt Protein Name: | Thymidine phosphorylase |
UniProt Synonym Protein Names: | Gliostatin; Platelet-derived endothelial cell growth factor; PD-ECGF; TdRPase |
UniProt Gene Name: | TYMP |
UniProt Entry Name: | TYPH_HUMAN |