TXNRD2 Antibody (PACO43592)
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주문- SKU:
- PACO43592
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TXNRD2 Antibody (PACO43592) |
Antibody SKU: | PACO43592 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:200-1:1000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Thioredoxin reductase 2, mitochondrial protein (100-310AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: Thioredoxin reductase 2, mitochondrial antibody at 6µg/ml. Lane 1: Mouse liver tissue. Lane 2: Mouse gonad tissue. Lane 3: Hela whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 57, 54, 47, 31 kDa. Observed band size: 57 kDa. | |
Immunohistochemistry of paraffin-embedded human endometrial cancer using PACO43592 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human breast cancer using PACO43592 at dilution of 1:100. |
Background: | Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling. |
Synonyms: | Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9) (Selenoprotein Z) (SelZ) (TR-beta) (Thioredoxin reductase TR3), TXNRD2, KIAA1652 TRXR2 |
UniProt Protein Function: | TXNRD2: Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Nucleotide Metabolism - pyrimidine; EC 1.8.1.9; Oxidoreductase Chromosomal Location of Human Ortholog: 22q11.21 Cellular Component: mitochondrial matrix; mitochondrion Molecular Function:FAD binding; protein binding; thioredoxin-disulfide reductase activity Biological Process: cell redox homeostasis; response to oxygen radical; response to reactive oxygen species |
NCBI Summary: | This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2013] |
UniProt Code: | Q9NNW7 |
NCBI GenInfo Identifier: | 182705230 |
NCBI Gene ID: | 10587 |
NCBI Accession: | Q9NNW7.3 |
UniProt Secondary Accession: | Q9NNW7,O95840, Q96IJ2, Q9H2Z5, Q9NZV3, Q9NZV4, Q9P2Y0 Q9P2Y1, Q9UQU8, |
UniProt Related Accession: | Q9NNW7 |
Molecular Weight: | 30,291 Da |
NCBI Full Name: | Thioredoxin reductase 2, mitochondrial |
NCBI Synonym Full Names: | thioredoxin reductase 2 |
NCBI Official Symbol: | TXNRD2 |
NCBI Official Synonym Symbols: | TR; TR3; SELZ; TRXR2; TR-BETA |
NCBI Protein Information: | thioredoxin reductase 2, mitochondrial |
UniProt Protein Name: | Thioredoxin reductase 2, mitochondrial |
UniProt Synonym Protein Names: | Selenoprotein Z; SelZ; TR-beta; Thioredoxin reductase TR3 |
Protein Family: | Thioredoxin reductase |
UniProt Gene Name: | TXNRD2 |
UniProt Entry Name: | TRXR2_HUMAN |
Antibodies | ELISA Kits |
Anti-TXNRD2 Antibody (CAB5490) | TRXR2 Colorimetric Cell-Based ELISA Kit |
Anti-TXNRD2 Antibody (CAB8884) | |
TXNRD2 Antibody (PACO06843) | |
TXNRD2 Antibody (PACO13005) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |