TWF2 Antibody (PACO15659)
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주문- SKU:
- PACO15659
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TWF2 Antibody (PACO15659) |
Antibody SKU: | PACO15659 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human TWF2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human endometrial carcinoma tissue, A172 cells, U937 cells, Primary antibody: PACO15659(TWF2 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO15659(TWF2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The protein encoded by this gene was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin (PTK9), a conserved actin monomer-binding protein. |
Synonyms: | twinfilin actin-binding protein 2 |
UniProt Protein Function: | A6r: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia. Belongs to the actin-binding proteins ADF family. Twinfilin subfamily. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 3p21.1 Cellular Component: stereocilium; cytoskeleton; growth cone; myofibril; lamellipodium; perinuclear region of cytoplasm; cytoplasm; filopodium Molecular Function:actin monomer binding; phosphatidylinositol-4,5-bisphosphate binding; protein kinase C binding; ATP binding Biological Process: cell projection organization and biogenesis; sequestering of actin monomers; negative regulation of actin filament polymerization; regulation of actin cytoskeleton organization and biogenesis; positive regulation of axon extension; regulation of microvillus length; barbed-end actin filament capping |
NCBI Summary: | The protein encoded by this gene was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin (PTK9), a conserved actin monomer-binding protein. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q6IBS0 |
NCBI GenInfo Identifier: | 94730596 |
NCBI Gene ID: | 11344 |
NCBI Accession: | Q6IBS0.2 |
UniProt Secondary Accession: | Q6IBS0,Q9Y3F5, |
UniProt Related Accession: | Q6IBS0 |
Molecular Weight: | 349 |
NCBI Full Name: | Twinfilin-2 |
NCBI Synonym Full Names: | twinfilin actin-binding protein 2 |
NCBI Official Symbol: | TWF2 |
NCBI Official Synonym Symbols: | A6r; A6RP; PTK9L; MSTP011 |
NCBI Protein Information: | twinfilin-2; A6-related protein; twinfilin-1-like protein; twinfilin, actin-binding protein, homolog 2; protein tyrosine kinase 9-like (A6-related protein); PTK9L protein tyrosine kinase 9-like (A6-related protein) |
UniProt Protein Name: | Twinfilin-2 |
UniProt Synonym Protein Names: | A6-related protein; hA6RP; Protein tyrosine kinase 9-like; Twinfilin-1-like protein |
Protein Family: | Twinfilin |
UniProt Gene Name: | TWF2 |
UniProt Entry Name: | TWF2_HUMAN |
Antibodies |
Anti-TWF2 Antibody (CAB13642) |
Anti-TWF2 Antibody (CAB5860) |
Anti-TWF2 Antibody (CAB19897)[KO Validated] |
Anti-TWF2 Antibody (CAB19898)[KO Validated] |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |