TTF2 Antibody (PACO18467)
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주문- SKU:
- PACO18467
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TTF2 Antibody (PACO18467) |
Antibody SKU: | PACO18467 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:5-1:20 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human TTF2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO18467(TTF2 Antibody) at dilution 1/5, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing. |
Synonyms: | transcription termination factor, RNA polymerase II |
UniProt Protein Function: | TTF2: DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing. Belongs to the SNF2/RAD54 helicase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Helicase; EC 3.6.4.-; Transcription regulation; EC 3.6.1.-; RNA splicing; DNA-binding Chromosomal Location of Human Ortholog: 1p22 Cellular Component: spliceosome; transcription elongation factor complex; cytoplasm Molecular Function:DNA-dependent ATPase activity; protein binding; DNA binding; zinc ion binding; ATP-dependent helicase activity; ATP binding Biological Process: regulation of transcription, DNA-dependent; RNA splicing; mRNA processing; termination of RNA polymerase II transcription; transcription termination |
NCBI Summary: | This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UNY4 |
NCBI GenInfo Identifier: | 119577071 |
NCBI Gene ID: | 8458 |
NCBI Accession: | EAW56667.1 |
UniProt Related Accession: | Q9UNY4 |
Molecular Weight: | 74kDa |
NCBI Full Name: | transcription termination factor, RNA polymerase II, isoform CRA_a |
NCBI Synonym Full Names: | transcription termination factor 2 |
NCBI Official Symbol: | TTF2 |
NCBI Official Synonym Symbols: | HuF2; ZGRF6 |
NCBI Protein Information: | transcription termination factor 2 |
UniProt Protein Name: | Transcription termination factor 2 |
UniProt Synonym Protein Names: | Lodestar homolog; RNA polymerase II termination factor; Transcription release factor 2 |
Protein Family: | Transcription termination factor |
UniProt Gene Name: | TTF2 |
UniProt Entry Name: | TTF2_HUMAN |
Antibodies | ELISA Kits |
Anti-TTF2 Antibody (CAB7751) | Human TTF2 ELISA Kit |
TTF2 Antibody (PACO12976) | Human Transcription termination factor 2 (TTF2) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |