TTC5 Antibody (PACO38210)
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주문- SKU:
- PACO38210
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TTC5 Antibody (PACO38210) |
Antibody SKU: | PACO38210 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Tetratricopeptide repeat protein 5 protein (201-440AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: TTC5 antibody at 6µg/ml. Lane 1: HepG2 whole cell lysate. Lane 2: A549 whole cell lysate. Lane 3: MCF-7 whole cell lysate. Lane 4: Mouse kidney tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 49 kDa. Observed band size: 49 kDa. |
Background: | Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2. |
Synonyms: | Tetratricopeptide repeat protein 5 (TPR repeat protein 5) (Stress-responsive activator of p300) (Strap), TTC5 |
UniProt Protein Function: | TTC5: Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 14q11.2 Cellular Component: nucleoplasm; cytoplasm Molecular Function:DNA binding; chromatin binding Biological Process: positive regulation of transcription from RNA polymerase II promoter; DNA repair |
UniProt Code: | Q8N0Z6 |
NCBI GenInfo Identifier: | 67462006 |
NCBI Gene ID: | |
NCBI Accession: | Q8N0Z6.1 |
UniProt Secondary Accession: | Q8N0Z6,Q99LG4, Q5BK48, |
Molecular Weight: | 48,928 Da |
NCBI Full Name: | Tetratricopeptide repeat protein 5 |
UniProt Protein Name: | Tetratricopeptide repeat protein 5 |
UniProt Synonym Protein Names: | Stress-responsive activator of p300; Strap |
Protein Family: | Tetratricopeptide repeat protein |
UniProt Gene Name: | TTC5 |
UniProt Entry Name: | TTC5_HUMAN |
Antibodies |
Anti-TTC5 Antibody (CAB13232) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |