TSTA3 Antibody (PACO12969)
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주문- SKU:
- PACO12969
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TSTA3 Antibody (PACO12969) |
Antibody SKU: | PACO12969 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human TSTA3 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | tissue specific transplantation antigen P35B;TSTA3;FX;P35B;SDR4E1 ; |
UniProt Protein Function: | TSTA3: Two step NADP-dependent conversion of GDP-4-dehydro-6- deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. Belongs to the fucose synthase family. |
UniProt Protein Details: | Protein type:Oxidoreductase; Carbohydrate Metabolism - fructose and mannose; EC 1.1.1.271; Carbohydrate Metabolism - amino sugar and nucleotide sugar Chromosomal Location of Human Ortholog: 8q24.3 Cellular Component: cytoplasm Molecular Function:GDP-L-fucose synthase activity; electron carrier activity; isomerase activity; coenzyme binding; GDP-4-dehydro-D-rhamnose reductase activity Biological Process: leukocyte adhesion; cytolysis; GDP-mannose metabolic process; 'de novo' GDP-L-fucose biosynthetic process |
NCBI Summary: | Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q13630 |
NCBI GenInfo Identifier: | 13124123 |
NCBI Gene ID: | 7264 |
NCBI Accession: | Q13630.1 |
UniProt Secondary Accession: | Q13630,Q567Q9, Q9UDG7, B2R8Y7, D3DWK5, |
UniProt Related Accession: | Q13630 |
Molecular Weight: | 321 |
NCBI Full Name: | GDP-L-fucose synthase |
NCBI Synonym Full Names: | tissue specific transplantation antigen P35B |
NCBI Official Symbol: | TSTA3 |
NCBI Official Synonym Symbols: | FX; P35B; SDR4E1 |
NCBI Protein Information: | GDP-L-fucose synthase; 3-5 epimerase/4-reductase; red cell NADP(H)-binding protein; tissue specific transplantation antigen 3; GDP-4-keto-6-deoxy-D-mannose epimerase-reductase; GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; short chain dehydrogenase/reductase family 4E, member 1 |
UniProt Protein Name: | GDP-L-fucose synthase |
UniProt Synonym Protein Names: | GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; Protein FX; Red cell NADP(H)-binding protein; Short-chain dehydrogenase/reductase family 4E member 1 |
UniProt Gene Name: | TSTA3 |
UniProt Entry Name: | FCL_HUMAN |