TSPAN7 Antibody (PACO30858)
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주문- SKU:
- PACO30858
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TSPAN7 Antibody (PACO30858) |
Antibody SKU: | PACO30858 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Tetraspanin-7 protein (113-223AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunofluorescent analysis of HepG2 cells using PACO30858 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO30858 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human spleen tissue using PACO30858 at dilution of 1:100. |
Background: | May be involved in cell proliferation and cell motility. |
Synonyms: | Tetraspanin-7 (Tspan-7) (Cell surface glycoprotein A15) (Membrane component chromosome X surface marker 1) (T-cell acute lymphoblastic leukemia-associated antigen 1) (TALLA-1) (Transmembrane 4 superfamily member 2) (CD antigen CD231), TSPAN7, A15 DXS1692E MXS1 TM4SF2 |
UniProt Protein Function: | TSPAN7: a multi-pass membrane protein. Member of the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins apparently mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Defects in TSPAN7 are the cause of mental retardation X- linked type 58 (MRX58). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: Xp11.4 Cellular Component: integral to plasma membrane Biological Process: viral reproduction Disease: Mental Retardation, X-linked 58 |
NCBI Summary: | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. [provided by RefSeq, Jul 2008] |
UniProt Code: | P41732 |
NCBI GenInfo Identifier: | 17380550 |
NCBI Gene ID: | 7102 |
NCBI Accession: | P41732.2 |
UniProt Secondary Accession: | P41732,Q8WVG5, Q9UEY9, B2R5W7, D3DWB1, |
UniProt Related Accession: | P41732 |
Molecular Weight: | 27kDa |
NCBI Full Name: | Tetraspanin-7 |
NCBI Synonym Full Names: | tetraspanin 7 |
NCBI Official Symbol: | TSPAN7 |
NCBI Official Synonym Symbols: | A15; MXS1; CD231; MRX58; CCG-B7; TM4SF2; TALLA-1; TM4SF2b; DXS1692E |
NCBI Protein Information: | tetraspanin-7; tspan-7; CD231 antigen; tetraspanin protein; transmembrane protein A15; cell surface glycoprotein A15; transmembrane 4 superfamily 2b; transmembrane 4 superfamily member 2; membrane component chromosome X surface marker 1; membrane component, X chromosome, surface marker 1; T-cell acute lymphoblastic leukemia associated antigen 1; T-cell acute lymphoblastic leukemia-associated antigen 1 |
UniProt Protein Name: | Tetraspanin-7 |
UniProt Synonym Protein Names: | Cell surface glycoprotein A15; Membrane component chromosome X surface marker 1; T-cell acute lymphoblastic leukemia-associated antigen 1; TALLA-1; Transmembrane 4 superfamily member 2; CD_antigen: CD231 |
UniProt Gene Name: | TSPAN7 |
UniProt Entry Name: | TSN7_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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