TRIM69 Antibody (PACO17007)
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주문- SKU:
- PACO17007
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TRIM69 Antibody (PACO17007) |
Antibody SKU: | PACO17007 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human TRIM69 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO17007(TRIM69 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
Synonyms: | tripartite motif containing 69 |
UniProt Protein Function: | TRIM69: May play a role in apoptosis. Belongs to the TRIM/RBCC family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 15q21.1 Cellular Component: cytoplasm; cytosol; nuclear speck; nucleus; plasma membrane Molecular Function:protein binding; ubiquitin-protein ligase activity Biological Process: protein polyubiquitination |
NCBI Summary: | This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q86WT6 |
NCBI GenInfo Identifier: | 229462760 |
NCBI Gene ID: | 140691 |
NCBI Accession: | Q86WT6.2 |
UniProt Secondary Accession: | Q86WT6,Q309B0, Q4G1A5, Q6W897, Q8IYY3, Q8WY16, Q8WY17 A8MX03, |
UniProt Related Accession: | Q86WT6 |
Molecular Weight: | 32,068 Da |
NCBI Full Name: | E3 ubiquitin-protein ligase TRIM69 |
NCBI Synonym Full Names: | tripartite motif containing 69 |
NCBI Official Symbol: | TRIM69 |
NCBI Official Synonym Symbols: | Trif; HSD34; RNF36; HSD-34 |
NCBI Protein Information: | E3 ubiquitin-protein ligase TRIM69 |
UniProt Protein Name: | E3 ubiquitin-protein ligase TRIM69 |
UniProt Synonym Protein Names: | RFP-like domain-containing protein trimless; RING finger protein 36; Tripartite motif-containing protein 69 |
Protein Family: | E3 ubiquitin-protein ligase |
UniProt Gene Name: | TRIM69 |
UniProt Entry Name: | TRI69_HUMAN |