TRIM26 Antibody (PACO60016)
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주문- SKU:
- PACO60016
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TRIM26 Antibody (PACO60016) |
Antibody SKU: | PACO60016 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Tripartite motif-containing protein 26 protein (151-270AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
IHC image of PACO60016 diluted at 1:300 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | cytosol, DNA binding, metal ion binding, innate immune response, interferon-gamma-mediated signaling pathway, negative regulation of viral entry into host cell, negative regulation of viral release from host cell, positive regulation of sequence-specific DNA binding transcription factor activity |
Synonyms: | Tripartite motif-containing protein 26 (EC 2.3.2.27) (acid, finger protein) (AFP) (RING finger protein 95) (Zinc finger protein 173), TRIM26, RNF95 ZNF173 |
UniProt Protein Function: | TRIM26: is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011] |
UniProt Protein Details: | Protein type:DNA-binding; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: cytosol Molecular Function:protein binding Biological Process: innate immune response; negative regulation of virion penetration into host cell; positive regulation of transcription factor activity |
NCBI Summary: | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011] |
UniProt Code: | Q12899 |
NCBI GenInfo Identifier: | 17380344 |
NCBI Gene ID: | 7726 |
NCBI Accession: | Q12899.1 |
UniProt Secondary Accession: | Q12899,Q5SRL2, A6NG96, |
UniProt Related Accession: | Q12899 |
Molecular Weight: | 62,166 Da |
NCBI Full Name: | Tripartite motif-containing protein 26 |
NCBI Synonym Full Names: | tripartite motif containing 26 |
NCBI Official Symbol: | TRIM26 |
NCBI Official Synonym Symbols: | AFP; RNF95; ZNF173 |
NCBI Protein Information: | tripartite motif-containing protein 26 |
UniProt Protein Name: | Tripartite motif-containing protein 26 |
UniProt Synonym Protein Names: | Acid finger protein; AFP; RING finger protein 95; Zinc finger protein 173 |
Protein Family: | Tripartite motif-containing protein |
UniProt Gene Name: | TRIM26 |
UniProt Entry Name: | TRI26_HUMAN |
Antibodies |
Anti-TRIM26 Antibody (CAB15332) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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