TRHR Antibody (PACO57000)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO57000
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TRHR Antibody (PACO57000) |
Antibody SKU: | PACO57000 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Thyrotropin-releasing hormone receptor protein (320-398AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunofluorescence staining of HepG2 cells with PACO57000 at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. |
Synonyms: | Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberin receptor), TRHR |
UniProt Protein Function: | TRHR: Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 8q23 Cellular Component: integral to plasma membrane; plasma membrane |
NCBI Summary: | This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011] |
UniProt Code: | P34981 |
NCBI GenInfo Identifier: | 464921 |
NCBI Gene ID: | 7201 |
NCBI Accession: | P34981.1 |
UniProt Secondary Accession: | P34981,Q2M339, |
UniProt Related Accession: | P34981 |
Molecular Weight: | 45,085 Da |
NCBI Full Name: | Thyrotropin-releasing hormone receptor |
NCBI Synonym Full Names: | thyrotropin releasing hormone receptor |
NCBI Official Symbol: | TRHR |
NCBI Official Synonym Symbols: | TRH-R |
NCBI Protein Information: | thyrotropin-releasing hormone receptor |
UniProt Protein Name: | Thyrotropin-releasing hormone receptor |
UniProt Synonym Protein Names: | Thyroliberin receptor |
Protein Family: | Thyrotropin-releasing hormone receptor |
UniProt Gene Name: | TRHR |
UniProt Entry Name: | TRFR_HUMAN |