UniProt Protein Function: | EHOC-1: a transport protein that may play role in vesicular transport from endoplasmic reticulum to Golgi. Part of the multisubunit TRAPP (transport protein particle) complex. Localizes in cis-Golgi complexes. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: integral to membrane Molecular Function:protein binding; sodium ion transmembrane transporter activity Biological Process: intra-Golgi vesicle-mediated transport; sodium ion transport |
NCBI Summary: | The protein encoded by this gene is a transmembrane protein found in the cis-Golgi complex. The encoded protein is part of the multisubunit transport protein particle (TRAPP) complex and may be involved in vesicular transport from the endoplasmic reticulum to the Golgi. Mutations in this gene could be responsible for the Unverricht-Lundborg type of progressive myoclonus epilepsy, or for autoimmune polyglandular disease type 1. [provided by RefSeq, Jul 2008] |
UniProt Code: | P48553 |
NCBI GenInfo Identifier: | 12644285 |
NCBI Gene ID: | 7109 |
NCBI Accession: | P48553.2 |
UniProt Secondary Accession: | P48553,Q3MIR2, Q86SI7, Q9UMD4, Q9Y4L3, |
UniProt Related Accession: | P48553 |
Molecular Weight: | 142kDa |
NCBI Full Name: | Trafficking protein particle complex subunit 10 |
NCBI Synonym Full Names: | trafficking protein particle complex 10 |
NCBI Official Symbol: | TRAPPC10 |
NCBI Official Synonym Symbols: | EHOC1; GT334; TMEM1; TRS30; EHOC-1; TRS130 |
NCBI Protein Information: | trafficking protein particle complex subunit 10; TRAPP subunit TMEM1; TRAPP 130 kDa subunit; transmembrane protein 1; transport protein particle subunit TMEM1; epilepsy holoprosencephaly candidate 1 protein; epilepsy holoprosencephaly candidate-1 protein; trafficking protein particle complex subunit 130; trafficking protein particle complex subunit TMEM1 |
UniProt Protein Name: | Trafficking protein particle complex subunit 10 |
UniProt Synonym Protein Names: | Epilepsy holoprosencephaly candidate 1 protein; EHOC-1; Protein GT334; Trafficking protein particle complex subunit TMEM1; Transport protein particle subunit TMEM1; TRAPP subunit TMEM1 |
Protein Family: | Trafficking protein particle complex |
UniProt Gene Name: | TRAPPC10 |
UniProt Entry Name: | TPC10_HUMAN |