TNFRSF9 Antibody (PACO55058)
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주문- SKU:
- PACO55058
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TNFRSF9 Antibody (PACO55058) |
Antibody SKU: | PACO55058 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Tumor necrosis factor receptor superfamily member 9 protein (24-186AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: HepG2 whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate. All lanes: TNFRSF9 antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 28 kDa. Observed band size: 65 kDa. | |
Immunofluorescent analysis of A549 cells using PACO55058 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. |
Synonyms: | Tumor necrosis factor receptor superfamily member 9 (4-1BB ligand receptor) (CDw137) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD antigen CD137), TNFRSF9, CD137 ILA |
UniProt Protein Function: | TNFRSF9: Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 1p36 Cellular Component: extracellular space; integral to plasma membrane; external side of plasma membrane Molecular Function:cytokine binding; receptor activity Biological Process: negative regulation of cell proliferation; apoptosis |
NCBI Summary: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q07011 |
NCBI GenInfo Identifier: | 728738 |
NCBI Gene ID: | 3604 |
NCBI Accession: | Q07011.1 |
UniProt Related Accession: | Q07011,AAB34924 |
Molecular Weight: | 27,899 Da |
NCBI Full Name: | Tumor necrosis factor receptor superfamily member 9 |
NCBI Synonym Full Names: | tumor necrosis factor receptor superfamily, member 9 |
NCBI Official Symbol: | TNFRSF9 |
NCBI Official Synonym Symbols: | ILA; 4-1BB; CD137; CDw137 |
NCBI Protein Information: | tumor necrosis factor receptor superfamily member 9; CD137 antigen; T cell antigen ILA; T-cell antigen ILA; 4-1BB ligand receptor; homolog of mouse 4-1BB; receptor protein 4-1BB; T-cell antigen 4-1BB homolog; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63 |
UniProt Protein Name: | Tumor necrosis factor receptor superfamily member 9 |
UniProt Synonym Protein Names: | 4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA; CD_antigen: CD137 |
UniProt Gene Name: | TNFRSF9 |
UniProt Entry Name: | TNR9_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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