TLR3 Antibody (PACO15597)
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주문- SKU:
- PACO15597
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TLR3 Antibody (PACO15597) |
Antibody SKU: | PACO15597 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human TLR3 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO15597(TLR3 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15597(TLR3 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. |
Synonyms: | toll-like receptor 3 |
UniProt Code: | O15455 |
NCBI GenInfo Identifier: | 20140422 |
NCBI Gene ID: | 7098 |
NCBI Accession: | O15455.1 |
UniProt Secondary Accession: | O15455,Q4VAL2, Q504W0, B2RAI7, B7Z7K0, E6Y0F0, E6Y0F1 E9PGH4, |
UniProt Related Accession: | O15455 |
Molecular Weight: | 72,937 Da |
NCBI Full Name: | Toll-like receptor 3 |
NCBI Synonym Full Names: | toll like receptor 3 |
NCBI Official Symbol: | TLR3 |
NCBI Official Synonym Symbols: | CD283; IIAE2 |
NCBI Protein Information: | toll-like receptor 3 |
UniProt Protein Name: | Toll-like receptor 3 |
UniProt Synonym Protein Names: | CD_antigen: CD283 |
Protein Family: | Toll-like receptor |
UniProt Gene Name: | TLR3 |
Antibodies | ELISA Kits |
Anti-TLR3 Antibody (CAB11778) | Human Toll-like receptor 3 (TLR3) ELISA Kit |
Anti-TLR3 Antibody (CAB1449) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |