THOC7 Antibody (PACO12743)
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주문- SKU:
- PACO12743
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | THOC7 Antibody (PACO12743) |
Antibody SKU: | PACO12743 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human THOC7 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | THO complex 7 homolog (Drosophila);THOC7;FLJ23445;NIF3L1BP1;fSAP24 ; |
UniProt Protein Function: | THOC7: Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and ALYREF/THOC4. Belongs to the THOC7 family. |
UniProt Protein Details: | Protein type:RNA splicing; Spliceosome Chromosomal Location of Human Ortholog: 3p14.1 Cellular Component: cytoplasm; nuclear chromosome, telomeric region; nucleoplasm; nucleus Molecular Function:nucleic acid binding; protein binding Biological Process: intronless viral mRNA export from host nucleus; mRNA 3'-end processing; mRNA export from nucleus; RNA elongation from RNA polymerase II promoter; RNA export from nucleus; termination of RNA polymerase II transcription |
UniProt Code: | Q6I9Y2 |
NCBI GenInfo Identifier: | 229462996 |
NCBI Gene ID: | 80145 |
NCBI Accession: | Q6I9Y2.3 |
UniProt Secondary Accession: | Q6I9Y2,Q6P1L3, Q8WUF2, Q9H5H0, |
UniProt Related Accession: | Q6I9Y2 |
Molecular Weight: | 23,743 Da |
NCBI Full Name: | THO complex subunit 7 homolog |
NCBI Synonym Full Names: | THO complex 7 |
NCBI Official Symbol: | THOC7 |
NCBI Official Synonym Symbols: | fSAP24; hTREX30; NIF3L1BP1 |
NCBI Protein Information: | THO complex subunit 7 homolog |
UniProt Protein Name: | THO complex subunit 7 homolog |
UniProt Synonym Protein Names: | Functional spliceosome-associated protein 24; fSAP24; Ngg1-interacting factor 3-like protein 1-binding protein 1; NIF3L1-binding protein 1; hTREX30 |
Protein Family: | THO complex |
UniProt Gene Name: | THOC7 |
UniProt Entry Name: | THOC7_HUMAN |