THAP12 Antibody (PACO29176)
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주문- SKU:
- PACO29176
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | THAP12 Antibody (PACO29176) |
Antibody SKU: | PACO29176 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human 52 kDa repressor of the inhibitor of the protein kinase protein (612-761AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: THAP12 antibody at 10µg/ml + HepG2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 88, 57 kDa Observed band size: 88 kDa . | |
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO29176 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human lung tissue using PACO29176 at dilution of 1:100. |
Background: | Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth. |
Synonyms: | 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12), THAP12, DAP4 P52RIPK PRKRIR THAP0 |
UniProt Protein Function: | PRKRIR: Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR- inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Protein kinase, regulatory subunit; Cell cycle regulation Chromosomal Location of Human Ortholog: 11q13.5 Cellular Component: nucleus Molecular Function:protein dimerization activity; DNA binding; metal ion binding Biological Process: negative regulation of cell proliferation; response to stress; signal transduction |
UniProt Code: | O43422 |
NCBI GenInfo Identifier: | 12643558 |
NCBI Gene ID: | 5612 |
NCBI Accession: | O43422.2 |
UniProt Secondary Accession: | O43422,Q9CUX1, |
UniProt Related Accession: | O43422 |
Molecular Weight: | 1137 |
NCBI Full Name: | 52 kDa repressor of the inhibitor of the protein kinase |
NCBI Synonym Full Names: | protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) |
NCBI Official Symbol: | PRKRIR |
NCBI Official Synonym Symbols: | DAP4; THAP0; THAP12; P52rIPK |
NCBI Protein Information: | 52 kDa repressor of the inhibitor of the protein kinase; THAP domain containing 12; death-associated protein 4; p58IPK-interacting protein; inhibitor of protein kinase PKR; THAP domain-containing protein 0; 58 kDa interferon-induced protein kinase-interac |
UniProt Protein Name: | 52 kDa repressor of the inhibitor of the protein kinase |
UniProt Synonym Protein Names: | 58 kDa interferon-induced protein kinase-interacting protein; p58IPK-interacting protein; Death-associated protein 4; THAP domain-containing protein 0 |
Protein Family: | Dipeptidyl aminopeptidase |
UniProt Gene Name: | PRKRIR |
UniProt Entry Name: | P52K_HUMAN |
Antibodies |
Anti-THAP12 Antibody (CAB15085) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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