TFPI2 Antibody (PACO43342)
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주문- SKU:
- PACO43342
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TFPI2 Antibody (PACO43342) |
Antibody SKU: | PACO43342 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Tissue factor pathway inhibitor 2 protein (23-235AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human breast cancer using PACO43342 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO43342 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO43342 at dilution of 1:100. |
Background: | May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin. |
Synonyms: | Tissue factor pathway inhibitor 2 (TFPI-2) (Placental protein 5) (PP5), TFPI2 |
UniProt Protein Function: | TFPI2: May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 7q22 Cellular Component: proteinaceous extracellular matrix; nucleus Molecular Function:serine-type endopeptidase inhibitor activity; extracellular matrix structural constituent Biological Process: blood coagulation |
NCBI Summary: | This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |
UniProt Code: | P48307 |
NCBI GenInfo Identifier: | 1351226 |
NCBI Gene ID: | 7980 |
NCBI Accession: | P48307.1 |
UniProt Secondary Accession: | P48307,Q66ME8, Q8NAK6, Q9UC86, |
UniProt Related Accession: | P48307 |
Molecular Weight: | 25,796 Da |
NCBI Full Name: | Tissue factor pathway inhibitor 2 |
NCBI Synonym Full Names: | tissue factor pathway inhibitor 2 |
NCBI Official Symbol: | TFPI2 |
NCBI Official Synonym Symbols: | PP5; REF1; TFPI-2 |
NCBI Protein Information: | tissue factor pathway inhibitor 2; placental protein 5; retinal pigment epithelium cell factor 1 |
UniProt Protein Name: | Tissue factor pathway inhibitor 2 |
UniProt Synonym Protein Names: | Placental protein 5; PP5 |
Protein Family: | Tissue factor pathway inhibitor |
UniProt Gene Name: | TFPI2 |
UniProt Entry Name: | TFPI2_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |