TCEB3 Antibody (PACO12670)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO12670
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TCEB3 Antibody (PACO12670) |
Antibody SKU: | PACO12670 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human TCEB3 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A);TCEB3;FLJ38760;FLJ42849;SIII;TCEB3A ; |
UniProt Protein Function: | TCEB3: SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). Heterotrimer of an A (A1, A2 or A3), B and C subunit. The C subunit mediates the binding of the elongin BC complex to subunit A. |
UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 1p36.1 Cellular Component: nucleoplasm; extracellular space; cytoplasm; integral to membrane; nucleus Molecular Function:DNA binding Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; viral reproduction; positive regulation of viral transcription; RNA elongation from RNA polymerase II promoter; gene expression |
NCBI Summary: | This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q14241 |
NCBI GenInfo Identifier: | 294862430 |
NCBI Gene ID: | 6924 |
NCBI Accession: | Q14241.2 |
UniProt Related Accession: | Q14241 |
Molecular Weight: | ~ 105kDa |
NCBI Full Name: | Elongin-A |
NCBI Synonym Full Names: | elongin A |
NCBI Official Symbol: | ELOA |
NCBI Official Synonym Symbols: | SIII; TCEB3; TCEB3A; SIII p110 |
NCBI Protein Information: | elongin-A |
UniProt Protein Name: | Transcription elongation factor B polypeptide 3 |
UniProt Synonym Protein Names: | Elongin 110 kDa subunit; Elongin-A; EloA; RNA polymerase II transcription factor SIII subunit A1; SIII p110 |
Protein Family: | Protein |
UniProt Gene Name: | TCEB3 |
UniProt Entry Name: | ELOA1_HUMAN |