TAL1 (Ab-122) Antibody (PACO21631)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO21631
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | TAL1 (Ab-122) Antibody (PACO21631) |
Antibody SKU: | PACO21631 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized non-phosphopeptide derived from human TAL-1 around the phosphorylation site of serine 122 (Q-L-S(p)-P-P). |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from Jurkat cells, treated with PMA (125ng/ml, 30mins), using TAL-1 (Ab-122) antibody. |
Background: | Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation By similarity. Gregory S.G., Nature 441:315-321(2006). |
Synonyms: | T-cell acute lymphocytic leukemia protein 1; SCL; TCL5; |
UniProt Protein Function: | TAL1: a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2. |
UniProt Protein Details: | Protein type:DNA-binding; Oncoprotein; Transcription factor Chromosomal Location of Human Ortholog: 1p32 Cellular Component: histone deacetylase complex; nuclear chromatin; nucleus; transcription factor complex Molecular Function:chromatin binding; enzyme binding; histone deacetylase binding; protein binding; transcription factor activity Biological Process: basophil differentiation; cell fate commitment; embryonic hemopoiesis; erythrocyte differentiation; hemopoiesis; megakaryocyte differentiation; positive regulation of cell division; positive regulation of chromatin assembly or disassembly; positive regulation of erythrocyte differentiation; positive regulation of mitotic cell cycle; positive regulation of protein complex assembly; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter Disease: Leukemia, Acute Lymphoblastic |
UniProt Code: | P17542 |
NCBI GenInfo Identifier: | 134305 |
NCBI Gene ID: | 6886 |
NCBI Accession: | P17542.2 |
UniProt Secondary Accession: | P17542,D3DQ24, |
UniProt Related Accession: | P17542 |
Molecular Weight: | 16,548 Da |
NCBI Full Name: | T-cell acute lymphocytic leukemia protein 1 |
NCBI Synonym Full Names: | TAL bHLH transcription factor 1, erythroid differentiation factor |
NCBI Official Symbol: | TAL1 |
NCBI Official Synonym Symbols: | SCL; TCL5; tal-1; bHLHa17 |
NCBI Protein Information: | T-cell acute lymphocytic leukemia protein 1 |
UniProt Protein Name: | T-cell acute lymphocytic leukemia protein 1 |
UniProt Synonym Protein Names: | Class A basic helix-loop-helix protein 17; bHLHa17; Stem cell protein; T-cell leukemia/lymphoma protein 5 |
Protein Family: | Transaldolase |
UniProt Gene Name: | TAL1 |
UniProt Entry Name: | TAL1_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |