TAGLN2 Antibody (PACO44363)
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주문- SKU:
- PACO44363
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TAGLN2 Antibody (PACO44363) |
Antibody SKU: | PACO44363 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Transgelin-2 protein (1-199AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: TAGLN2 antibody at 2.64µg/ml. Lane 1: 293T whole cell lysate. Lane 2: K562 whole cell lysate. Lane 3: MCF-7 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 23, 25 kDa. Observed band size: 23 kDa.. | |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO44363 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO44363 at dilution of 1:100. |
Background: | extracellular exosome, vesicle, epithelial cell differentiation |
Synonyms: | Transgelin-2 (Epididymis tissue protein Li 7e) (SM22-α homolog), TAGLN2, KIAA0120 |
UniProt Protein Function: | TAGLN2: a cytoskeletal protein of the calponin family. One of the earliest markers of differentiated smooth muscle. Expressed in the smooth, cardiac, and skeletal muscle cells during early embryogenesis. Becomes restricted to vascular and visceral smooth muscle cells in late fetal development and adulthood. Its expression is abolished by activated Ras. Ras-dependent and Ras-independent mechanisms can cause the down-regulation of transgelin in breast and colon cancer cells lines and tumor samples. |
UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 1q21-q25 Cellular Component: vesicle Molecular Function:protein binding Biological Process: epithelial cell differentiation |
NCBI Summary: | The protein encoded by this gene is similar to the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The specific function of this protein has not yet been determined, although it is thought to be a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2013] |
UniProt Code: | P37802 |
NCBI GenInfo Identifier: | 586000 |
NCBI Gene ID: | 8407 |
NCBI Accession: | P37802.3 |
UniProt Secondary Accession: | P37802,Q5JRQ6, Q5JRQ7, Q6FGI1, Q9BUH5, Q9H4P0, E9KL39 |
UniProt Related Accession: | P37802 |
Molecular Weight: | 24,454 Da |
NCBI Full Name: | Transgelin-2 |
NCBI Synonym Full Names: | transgelin 2 |
NCBI Official Symbol: | TAGLN2 |
NCBI Official Synonym Symbols: | HA1756 |
NCBI Protein Information: | transgelin-2 |
UniProt Protein Name: | Transgelin-2 |
UniProt Synonym Protein Names: | Epididymis tissue protein Li 7e; SM22-alpha homolog |
Protein Family: | Transgelin |
UniProt Gene Name: | TAGLN2 |
UniProt Entry Name: | TAGL2_HUMAN |
Antibodies | ELISA Kits |
Anti-TAGLN2 Antibody (CAB6761)[KO Validated] | Human Transgelin-2 / TAGLN2 ELISA Kit |
TAGLN2 Antibody (PACO12633) | Human Transgelin-2 (TAGLN2) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |