TAF15 Antibody (PACO01582)
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주문- SKU:
- PACO01582
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TAF15 Antibody |
Antibody SKU: | PACO01582 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human, Mouse |
Immunogen: | synthesized peptide derived from the Internal region of human TAF II p68. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | TAF15; RBP56; TAF2N; TATA-binding protein-associated factor 2N; 68 kDa TATA-binding protein-associated factor; TAF(II)68; TAFII68; RNA-binding protein 56 |
UniProt Protein Function: | TAF15: RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II). A chromosomal aberration involving TAF15/TAF2N is found in a form of extraskeletal myxoid chondrosarcomas (EMC). Translocation t(9;17)(q22;q11) with NR4A3. Belongs to the RRM TET family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:RNA-binding; Oncoprotein; Translation Chromosomal Location of Human Ortholog: 17q11.1-q11.2 Cellular Component: cytoplasm; nucleolus; nucleoplasm; nucleus Molecular Function:DNA binding; nucleotide binding; protein binding; zinc ion binding Biological Process: positive regulation of transcription, DNA-dependent Disease: Chondrosarcoma, Extraskeletal Myxoid |
NCBI Summary: | This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012] |
UniProt Code: | Q92804 |
NCBI GenInfo Identifier: | 8928305 |
NCBI Gene ID: | 8148 |
NCBI Accession: | Q92804.1 |
UniProt Secondary Accession: | Q92804,Q86X94, Q92751, B2R837, |
UniProt Related Accession: | Q92804 |
Molecular Weight: | 61,558 Da |
NCBI Full Name: | TATA-binding protein-associated factor 2N |
NCBI Synonym Full Names: | TATA-box binding protein associated factor 15 |
NCBI Official Symbol: | TAF15 |
NCBI Official Synonym Symbols: | Npl3; RBP56; TAF2N; TAFII68 |
NCBI Protein Information: | TATA-binding protein-associated factor 2N |
UniProt Protein Name: | TATA-binding protein-associated factor 2N |
UniProt Synonym Protein Names: | 68 kDa TATA-binding protein-associated factor; TAF(II)68; TAFII68; RNA-binding protein 56 |
Protein Family: | Transcription initiation factor |
UniProt Gene Name: | TAF15 |
UniProt Entry Name: | RBP56_HUMAN |