SYT11 Antibody (PACO43839)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO43839
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SYT11 Antibody (PACO43839) |
Antibody SKU: | PACO43839 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:200-1:1000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Synaptotagmin-11 protein (37-200AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: SYT11 antibody at 14µg/ml. Lane 1: COLO205 whole cell lysate. Lane 2: Mouse skeletal muscle tissue. Lane 3: MCF-7 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 48 kDa. Observed band size: 48 kDa. |
Background: | May be involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain or may serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. |
Synonyms: | Synaptotagmin-11 (Synaptotagmin XI) (SytXI), SYT11, KIAA0080 |
UniProt Protein Function: | SYT11: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Belongs to the synaptotagmin family. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 1q21.2 Cellular Component: synaptic vesicle; synaptic vesicle membrane; integral to plasma membrane; cell junction Molecular Function:protein binding; calcium-dependent phospholipid binding; transporter activity; calcium ion binding Biological Process: transport; negative regulation of neurotransmitter secretion |
NCBI Summary: | This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010] |
UniProt Code: | Q9BT88 |
NCBI GenInfo Identifier: | 15489165 |
NCBI Gene ID: | 23208 |
NCBI Accession: | AAH13690.1 |
UniProt Secondary Accession: | Q9BT88,Q14998, Q5W0D4, Q68CT5, Q8IXU3, Q96SU2, |
UniProt Related Accession: | Q9BT88 |
Molecular Weight: | 48,297 Da |
NCBI Full Name: | Synaptotagmin XI |
NCBI Synonym Full Names: | synaptotagmin XI |
NCBI Official Symbol: | SYT11 |
NCBI Official Synonym Symbols: | SYT12; sytXI |
NCBI Protein Information: | synaptotagmin-11; synaptotagmin 12 |
UniProt Protein Name: | Synaptotagmin-11 |
UniProt Synonym Protein Names: | Synaptotagmin XI; SytXI |
Protein Family: | Synaptotagmin |
UniProt Gene Name: | SYT11 |
UniProt Entry Name: | SYT11_HUMAN |