SYCP1 Antibody (PACO20407)
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주문- SKU:
- PACO20407
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SYCP1 Antibody (PACO20407) |
Antibody SKU: | PACO20407 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human SYCP1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO20407(SYCP1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The synaptonemal complex protein 1 (SCP-1), also known as SYCP1(A), SYN1(I) and HOM-TES-14, is a protein product of human chromosome 1p13-p12. SCP-1 is a major component of the transverse filaments of synaptonemal complexes and functions by pairing homologous chromosomes during meiotic prophase in spermatocytes, which is an essential step for the generation of haploid cells in meiosis I. SCP-1 is expressed in the testis, adult brain, some malignant gliomas, breast, renal cell and ovarian cancer. SCP-1 is known to be selectively expressed during the meiotic prophase of spermatocytes and shows cell cycle phase-independent nuclear expression in cancer cells. |
Synonyms: | synaptonemal complex protein 1 |
UniProt Protein Function: | SYCP1: Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. |
UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA); DNA-binding Chromosomal Location of Human Ortholog: 1p13.2 Cellular Component: synaptonemal complex Biological Process: meiotic recombination; spermatogenesis; synapsis; synaptonemal complex assembly |
UniProt Code: | Q15431 |
NCBI GenInfo Identifier: | 209572682 |
NCBI Gene ID: | 6847 |
NCBI Accession: | Q15431.2 |
UniProt Secondary Accession: | Q15431,O14963, Q5VXJ6, |
UniProt Related Accession: | Q15431 |
Molecular Weight: | 114kDa |
NCBI Full Name: | Synaptonemal complex protein 1 |
NCBI Synonym Full Names: | synaptonemal complex protein 1 |
NCBI Official Symbol: | SYCP1 |
NCBI Official Synonym Symbols: | CT8; SCP1; SCP-1; HOM-TES-14 |
NCBI Protein Information: | synaptonemal complex protein 1 |
UniProt Protein Name: | Synaptonemal complex protein 1 |
UniProt Synonym Protein Names: | Cancer/testis antigen 8; CT8 |
Protein Family: | Synaptonemal complex protein |
UniProt Gene Name: | SYCP1 |
Antibodies |
Anti-SYCP1 Antibody (CAB12139) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |