SV2C Antibody (PACO58937)
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주문- SKU:
- PACO58937
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SV2C Antibody (PACO58937) |
Antibody SKU: | PACO58937 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Synaptic vesicle glycoprotein 2C protein (459-524AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
IHC image of PACO58937 diluted at 1:300 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. | |
IHC image of PACO58937 diluted at 1:300 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity). |
Synonyms: | Synaptic vesicle glycoprotein 2C, SV2C, KIAA1054 |
UniProt Protein Function: | SV2C: Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles. Belongs to the major facilitator superfamily. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 5q13.3 Cellular Component: synaptic vesicle; synaptic vesicle membrane; integral to membrane; plasma membrane; cell junction Molecular Function:transmembrane transporter activity Biological Process: neurotransmitter transport; pathogenesis; transmembrane transport |
UniProt Code: | Q496J9 |
NCBI GenInfo Identifier: | 108860965 |
NCBI Gene ID: | 22987 |
NCBI Accession: | Q496J9.1 |
UniProt Secondary Accession: | Q496J9,Q496K1, Q9UPU8, |
UniProt Related Accession: | Q496J9 |
Molecular Weight: | 727 |
NCBI Full Name: | Synaptic vesicle glycoprotein 2C |
NCBI Synonym Full Names: | synaptic vesicle glycoprotein 2C |
NCBI Official Symbol: | SV2C |
NCBI Protein Information: | synaptic vesicle glycoprotein 2C; synaptic vesicle protein 2C |
UniProt Protein Name: | Synaptic vesicle glycoprotein 2C |
Protein Family: | Synaptic vesicle glycoprotein |
UniProt Gene Name: | SV2C |
UniProt Entry Name: | SV2C_HUMAN |