SUPT20H Antibody (PACO44637)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO44637
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SUPT20H Antibody (PACO44637) |
Antibody SKU: | PACO44637 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Transcription factor SPT20 homolog protein (580-779AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: SUPT20H antibody at 0.21µg/ml. Lane 1: Mouse lung tissue. Lane 2: Mouse kidney tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 86, 81, 89 kDa. Observed band size: 86 kDa.. | |
Immunohistochemistry of paraffin-embedded human testis tissue using PACO44637 at dilution of 1:100. |
Background: | Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail (By similarity). Required for starvation-induced ATG9A trafficking during autophagy. |
Synonyms: | Transcription factor SPT20 homolog (p38-interacting protein) (p38IP), SUPT20H, C13orf19 FAM48A |
UniProt Protein Function: | FAM48A: Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down- regulation of E-cadherin during gastrulation by regulating E- cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail. Required for starvation- induced ATG9A trafficking during autophagy. Belongs to the FAM48 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 13q13.3 Cellular Component: nucleolus Molecular Function:protein binding; transcription cofactor activity Biological Process: establishment and/or maintenance of chromatin architecture; autophagy; gastrulation |
UniProt Code: | Q8NEM7 |
NCBI GenInfo Identifier: | 334302791 |
NCBI Gene ID: | 55578 |
NCBI Accession: | Q8NEM7.2 |
UniProt Secondary Accession: | Q8NEM7,Q71RF3, Q9Y6A6, E7ER46, |
UniProt Related Accession: | Q8NEM7 |
Molecular Weight: | 779 |
NCBI Full Name: | Transcription factor SPT20 homolog |
NCBI Synonym Full Names: | suppressor of Ty 20 homolog (S. cerevisiae) |
NCBI Official Symbol: | SUPT20H |
NCBI Official Synonym Symbols: | C13; FP757; P38IP; SPT20; FAM48A; C13orf19 |
NCBI Protein Information: | transcription factor SPT20 homolog; protein FAM48A; tumor rejection antigen; family with sequence similarity 48, member A; transcription factor (p38 interacting protein) |
UniProt Protein Name: | Transcription factor SPT20 homolog |
UniProt Synonym Protein Names: | p38-interacting protein; p38IP |
Protein Family: | Transcription factor |
UniProt Gene Name: | SUPT20H |
UniProt Entry Name: | SP20H_HUMAN |