SUCLG1 Antibody (PACO12572)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO12572
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | SUCLG1 Antibody (PACO12572) |
Antibody SKU: | PACO12572 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human SUCLG1 |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | succinate-CoA ligase, α subunit;SUCLG1;FLJ21114;G-ALPHA;SUCLA1 ; |
UniProt Protein Function: | SUCLG1: Catalyzes the ATP- or GTP-dependent ligation of succinate and CoA to form succinyl-CoA. The nature of the beta subunit determines the nucleotide specificity. Heterodimer of an alpha and a beta subunit. Belongs to the succinate/malate CoA ligase alpha subunit family. |
UniProt Protein Details: | Protein type:Carbohydrate Metabolism - propanoate; Mitochondrial; EC 6.2.1.4; Carbohydrate Metabolism - citrate (TCA) cycle; EC 6.2.1.5; Ligase Chromosomal Location of Human Ortholog: 2p11.2 Cellular Component: mitochondrion; mitochondrial matrix; mitochondrial inner membrane; cytoplasm; plasma membrane Molecular Function:succinate-CoA ligase (GDP-forming) activity; GDP binding; GTP binding; ATP citrate synthase activity; protein heterodimerization activity; cofactor binding; succinate-CoA ligase (ADP-forming) activity Biological Process: cellular metabolic process; succinate metabolic process; tricarboxylic acid cycle; succinyl-CoA metabolic process Disease: Mitochondrial Dna Depletion Syndrome 9 (encephalomyopathic Type With Methylmalonic Aciduria) |
NCBI Summary: | This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion. [provided by RefSeq, Feb 2010] |
UniProt Code: | P53597 |
NCBI GenInfo Identifier: | 1122286 |
NCBI Gene ID: | 8802 |
NCBI Accession: | CAA92426.1 |
UniProt Secondary Accession: | P53597,Q9BWB0, Q9UNP6, |
UniProt Related Accession: | P53597 |
Molecular Weight: | 36,250 Da |
NCBI Full Name: | succinyl coenzyme A synthetase |
NCBI Synonym Full Names: | succinate-CoA ligase, alpha subunit |
NCBI Official Symbol: | SUCLG1 |
NCBI Official Synonym Symbols: | GALPHA; MTDPS9; SUCLA1 |
NCBI Protein Information: | succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; SCS-alpha; succinyl-CoA synthetase subunit alpha; succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial |
UniProt Protein Name: | Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial |
UniProt Synonym Protein Names: | Succinyl-CoA synthetase subunit alpha |
UniProt Gene Name: | SUCLG1 |
UniProt Entry Name: | SUCA_HUMAN |